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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Synthetic Applications of Intramolecular Aza-Wittig Reaction for the Preparation of Heterocyclic Compounds

Author(s): Francisco Palacios, Domitila Aparicio, Gloria Rubiales, Concepcion Alonso and Jesus M. de los Santos

Volume 13, Issue 8, 2009

Page: [810 - 828] Pages: 19

DOI: 10.2174/138527209788167196

Price: $65

Abstract

A review focused on recent advances in intramolecular aza-Wittig reaction of phosphazenes with several carbonyl or analogous compounds is reported. Phosphazenes afford intramolecular aza-Wittig reaction with different groups within the molecule as aldehydes, ketones, esters, thioesters, amides, anhydrides and sulfimides. One of the most important applications of this reaction is the synthesis of a wide range of heterocyclic compounds, ranging from simple monocyclic compounds to complex polycyclic and macrocyclic systems.

Keywords: Heterocyclic Compounds, synthesis, intramolecular aza-Wittig reaction, phosphazenes


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