Abstract
It is known that long lasting changes in cell volume are incompatible with cellular functions. In the present review, I discussed the role of cell volume on gene expression and protein synthesis as well as the importance of the renin angiotensin system on the regulation of cell volume in the failing heart. Moreover, the relationship between mechanical stretch, cell volume and the renin angiotensin system as well some translational studies are also described and their relevance to the prevention or reduction of cardiac damage during myocardial ischemia is emphasized.
Keywords: Cell volume, myocardial ischemia, renin, angiotensin II, angiotensin (1-7) intracrine, stretch
Current Cardiology Reviews
Title: Renin Angiotensin System as a Regulator of Cell Volume. Implications to Myocardial Ischemia
Volume: 5 Issue: 1
Author(s): Walmor C. De Mello
Affiliation:
Keywords: Cell volume, myocardial ischemia, renin, angiotensin II, angiotensin (1-7) intracrine, stretch
Abstract: It is known that long lasting changes in cell volume are incompatible with cellular functions. In the present review, I discussed the role of cell volume on gene expression and protein synthesis as well as the importance of the renin angiotensin system on the regulation of cell volume in the failing heart. Moreover, the relationship between mechanical stretch, cell volume and the renin angiotensin system as well some translational studies are also described and their relevance to the prevention or reduction of cardiac damage during myocardial ischemia is emphasized.
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Cite this article as:
De Mello C. Walmor, Renin Angiotensin System as a Regulator of Cell Volume. Implications to Myocardial Ischemia, Current Cardiology Reviews 2009; 5 (1) . https://dx.doi.org/10.2174/157340309787048149
DOI https://dx.doi.org/10.2174/157340309787048149 |
Print ISSN 1573-403X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6557 |
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