Ascorbic Acid in Postoperative Intensive Care Patients - Biochemical Aspects and Clinical Experience

Title: Ascorbic Acid in Postoperative Intensive Care Patients - Biochemical Aspects and Clinical Experience

Volume: 16 Issue: 2

Author(s): Andreas Rumelin

Affiliation:

• Department of Anesthesiology, Johannes Gutenberg University Mainz, Germany.,Germany

Keywords: Vitamin C, ascorbic acid, intensive care, ICU, metabolism, trauma, operation

Abstract: The transport mechanisms of ascorbic acid (AA) are described. The metabolism of AA and its function as an antioxidant are covered in some detail. Subsequently, indications for postoperative substitution are discussed. The supplementation of up to 300 mg of AA per day in postoperative intensive care unit patients during par-/enteral nutrition is recommended to prevent hypovitaminosis. It is not clear if this is the optimal dosage of AA in postoperative/-trauma patients. New aspects for an AA substitution are discussed.

Cite this article as:

Rumelin Andreas, Ascorbic Acid in Postoperative Intensive Care Patients - Biochemical Aspects and Clinical Experience, Current Medicinal Chemistry 2009; 16(2) . https://dx.doi.org/10.2174/092986709787002781