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Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Research Article

Dual-energy CT Virtual Non-Calcium Image is Beneficial for the Detection of Non-displaced Knee Fractures

Author(s): Yijie Fang, Chaoran Liu, Wen Yu, Yingying Zhan, Wenjuan Li, Jianchao Liang* and Guobin Hong*

Volume 19, Issue 10, 2023

Published on: 15 December, 2022

Article ID: e231122211146 Pages: 8

DOI: 10.2174/1573405619666221123100908

Price: $65

Abstract

Background: Early and accurate diagnosis is vital for avoiding the development of nondisplaced fractures to displaced fractures. Dual-energy CT (Computed Tomography) can detect bone marrow edema (BME), which may help to detect non-displaced fractures.

Aim: To evaluate the value of DECT (Dual-Energy Computed Tomography) VNCa (Virtual noncalcium) images for improving diagnostic performance and confidence in acute non-displaced knee fractures.

Methods: 125 patients with clinical suspicion of knee fractures underwent both DECT and MR. Conventional linear-blended CT and VNCa images were obtained from DECT. First, five readers with varying levels of experience evaluated the presence of fractures on conventional linear-blended CT and graded their diagnostic confidence on a scale of 1 to 10. Then BME with VNCa images was evaluated and compared with MR. Finally, the VNCa images combined with conventional linear-blended CT images were used to reassess the presence of fractures and diagnostic confidence. Diagnostic performance and matched pair analyses were performed.

Results: 20 non-displaced knee fractures were detected. The consistency test of VNCa images and MR by five radiologists showed Kappa values are 0.76, 0.79, 0.81,0.85,and 0.90,respectively. The diagnostic performance of all readers was improved when using VNCa images combined with conventional linear-blended CT compared with that with conventional linear-blended CT alone. Diagnostic confidence was improved with combined conventional linear-blended CT and VNCa images (median score:8,8,9,9, and 10, respectively) compared with conventional linear-blended CT alone (median score:7,7,8,9, and 9).

Conclusion: DECT VNCa images could improve the radiologists' diagnostic performance and confidence with varying levels of experience in the detection of non-displaced knee fractures.

Keywords: Dual-energy scanned projection radiography, knee, fracture, bone marrow, sensitivity, retrospective single-center study.

Graphical Abstract
[1]
Gosangi B, Mandell JC, Weaver MJ, et al. Bone marrow edema at dual-energy CT: A game changer in the emergency department. Radiographics 2020; 40(3): 859-74.
[http://dx.doi.org/10.1148/rg.2020190173] [PMID: 32364883]
[2]
Boks SS, Vroegindeweij D, Koes BW, Hunink MGM, Bierma-Zeinstra SMA. Follow-up of occult bone lesions detected at MR imaging: systematic review. Radiology 2006; 238(3): 853-62.
[http://dx.doi.org/10.1148/radiol.2382050062] [PMID: 16452394]
[3]
Reddy T, McLaughlin PD, Mallinson PI, et al. Detection of occult, undisplaced hip fractures with a dual-energy CT algorithm targeted to detection of bone marrow edema. Emerg Radiol 2015; 22(1): 25-9.
[http://dx.doi.org/10.1007/s10140-014-1249-6] [PMID: 24985783]
[4]
Kellock TT, Nicolaou S, Kim SS. Detection of bone marrow edema in nondisplaced hip fractures: Utility of a virtual unenhanced dual-energy CT. Appl Radiol 2017; 284: 798-805.
[http://dx.doi.org/10.1148/radiol.2017161063] [PMID: 28301779]
[5]
Wicky S, Blaser PF, Blanc CH, Leyvraz PF, Schnyder P, Meuli RA. Comparison between standard radiography and spiral CT with 3D reconstruction in the evaluation, classification and management of tibial plateau fractures. Eur Radiol 2000; 10(8): 1227-32.
[http://dx.doi.org/10.1007/s003300000326] [PMID: 10939479]
[6]
Johnson TRC, Krauß B, Sedlmair M, et al. Material differentiation by dual energy CT: initial experience. Eur Radiol 2007; 17(6): 1510-7.
[http://dx.doi.org/10.1007/s00330-006-0517-6] [PMID: 17151859]
[7]
Toepker M, Moritz T, Krauss B, et al. Virtual non-contrast in second-generation, dual-energy computed tomography: Reliability of attenuation values. Eur J Radiol 2012; 81(3): e398-405.
[http://dx.doi.org/10.1016/j.ejrad.2011.12.011] [PMID: 22236702]
[8]
Graser A, Johnson TRC, Bader M, et al. Dual energy CT characterization of urinary calculi: initial in vitro and clinical experience. Invest Radiol 2008; 43(2): 112-9.
[http://dx.doi.org/10.1097/RLI.0b013e318157a144] [PMID: 18197063]
[9]
Henes FO, Groth M, Bley TA, et al. Quantitative assessment of bone marrow attenuation values at MDCT: An objective tool for the detection of bone bruise related to occult sacral insufficiency fractures. Eur Radiol 2012; 22(10): 2229-36.
[http://dx.doi.org/10.1007/s00330-012-2472-8] [PMID: 22585406]
[10]
Nicolaou S, Liang T, Murphy DT. Dual-energy CT: A promising new technique for assessment of the musculoskeletal system. AJR Am J Roentgenol 2012; 199 (5 Suppl.): S78-86.
[http://dx.doi.org/10.2214/AJR.12.9117]
[11]
Biondi M, Vanzi E, De Otto G, et al. Water/cortical bone decomposition: A new approach in dual energy CT imaging for bone marrow oedema detection. A feasibility study. Phys Med 2016; 32(12): 1712-6.
[http://dx.doi.org/10.1016/j.ejmp.2016.08.004] [PMID: 27524684]
[12]
Guggenberger R, Gnannt R, Hodler J, et al. Diagnostic performance of dual-energy CT for the detection of traumatic bone marrow lesions in the ankle: Comparison with MR imaging. Radiology 2012; 264(1): 164-73.
[http://dx.doi.org/10.1148/radiol.12112217] [PMID: 22570505]
[13]
Son W, Park C, Jeong HS, Song YS, Lee IS. Bone marrow edema in non-traumatic hip: High accuracy of dual-energy CT with water-hydroxyapatite decomposition imaging. Eur Radiol 2020; 30(4): 2191-8.
[http://dx.doi.org/10.1007/s00330-019-06519-8] [PMID: 31822976]
[14]
Wang CK, Tsai JM, Chuang MT, Wang MT, Huang KY, Lin RM. Bone marrow edema in vertebral compression fractures: Detection with dual-energy CT. Radiology 2013; 269(2): 525-33.
[http://dx.doi.org/10.1148/radiol.13122577] [PMID: 23801776]
[15]
Barr MS, Anderson MW. The knee: Bone marrow abnormalities. Radiol Clin North Am 2002; 40(5): 1109-20.
[http://dx.doi.org/10.1016/S0033-8389(02)00051-9] [PMID: 12462471]
[16]
Pache G, Krauss B, Strohm P, et al. Dual-energy CT virtual noncalcium technique: Detecting posttraumatic bone marrow lesions--feasibility study. Radiology 2010; 256(2): 617-24.
[http://dx.doi.org/10.1148/radiol.10091230] [PMID: 20551186]
[17]
Karaca L, Yuceler Z, Kantarci M, et al. The feasibility of dual-energy CT in differentiation of vertebral compression fractures. Br J Radiol 2016; 89(1057): 20150300.
[http://dx.doi.org/10.1259/bjr.20150300] [PMID: 26537691]
[18]
Kaup M, Wichmann JL, Scholtz JE, et al. Dual-Energy CT–based display of bone marrow edema in osteoporotic vertebral compression fractures: Impact on diagnostic accuracy of radiologists with varying levels of experience in correlation to MR imaging. Radiology 2016; 280(2): 510-9.
[http://dx.doi.org/10.1148/radiol.2016150472] [PMID: 26928067]

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