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Current Drug Delivery

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ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

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Review Article

Promises of Molecular Pharmaceutics in the Development of Novel Drug Delivery Formulations

Author(s): Parveen Kumar, Benu Chaudhary, Vivek Jain, Sanjula Baboota, Palanisamy Shivanandy*, Khalid Saad Alharbi, Mohammed M Ghoneim, Sultan Alshehri, Syed Sarim Imam, Gaurav Gupta and Madan Mohan Gupta*

Volume 20, Issue 9, 2023

Published on: 13 December, 2022

Page: [1262 - 1274] Pages: 13

DOI: 10.2174/1567201820666221114113637

Price: $65

Abstract

Molecular pharmaceutics play a critical role in the drug delivery system, representing the direct interconnection of drug bioavailability with its molecular form. There is a diversity in the molecular structures by which it affects its properties, such as amorphous form, crystalline form, partialamorphous molecular dispersion, and disordered state. The active pharmaceutical ingredient (API) and the excipients utilized in the formulation process contain various divergent modes used in the formulation process. They include better formulations of any type to obtain good quality pharmaceutical products. This review reveals how the molecular states affect the API and are important in maintaining the quality of dosage forms. Furthermore, the physio-chemical properties of the components and various pharmaceutical approaches employed in the formulation of dosage forms are studied from the point of view of molecular pharmaceutics.

Keywords: Molecular pharmaceutics, drug delivery, active pharmaceutical ingredients, formulation, polymer, microparticles.

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