Generic placeholder image

Recent Advances in Electrical & Electronic Engineering

Editor-in-Chief

ISSN (Print): 2352-0965
ISSN (Online): 2352-0973

Review Article

Application of 3D Printing Technology in the Medical Field

Author(s): Bingwei Gao*, Hongjian Zhao, Hongtao Yu, Yihan Lin, Jun Liu and Jiawei Wang

Volume 15, Issue 8, 2022

Published on: 25 October, 2022

Page: [621 - 633] Pages: 13

DOI: 10.2174/2352096515666221006142356

Price: $65

Abstract

Background: 3D printing technology is widely used, with its application majorly prevailing in the medical field.

Objective: In this paper, the applications of 3D printing technology in the medical field are classified and summarized, and their characteristics are introduced.

Methods: This paper mainly summarizes the contribution of 3D printing technology to the field of medicine, as well as four applications of 3D printing technology in medicine, and also introduces some examples of clinical application of 3D printing.

Results: 3D printing has proved to be an emerging art and a new innovation. It has a variety of different medical applications. Because of its limitations, it is not routinely used in clinical practice. However, it will be open to the public in the near future due to technological advances. It will provide new opportunities for every healthcare provider and seeker, and it will become a modern technology for innovative medical practices.

Conclusion: 3D printing technology has been significantly developed and applied to oral cavity, implants and even human organs in the medical fieldand shows a vigorous development trend. It is believed that this technology will significantly benefit mankind in the future.

Keywords: 3D printing, technology, medical field, stomatology, artificial joint, organ model.

Graphical Abstract
[1]
S.V. Murphy, and A. Atala, "3D bioprinting of tissues and organs", Nat. Biotechnol., vol. 32, no. 8, pp. 773-785, 2014.
[http://dx.doi.org/10.1038/nbt.2958] [PMID: 25093879]
[2]
D.X. Lv, "The characteristics and application of 3D printing", Intelligence. no. 20, pp. 247, 2013.
[3]
C.L. Ventola, "Medical applications for 3D printi-ng: Current and projected uses", P T, vol. 39, no. 10, pp. 704-711, 2014.
[PMID: 25336867]
[4]
L. Dong, "Application of 3D printing technology in the field of construction", Inform. Record. Mater., vol. 22, pp. 111-113, 2021.
[5]
L.Z. Tan, and F. Fang, "3D printing technology and its application in aerospace", Tact. Missile Technol, no. 4, pp. 1-7, 2016.
[6]
G. Zhu, E. Lin, Z.J. Lin, Y. Li, Z.F. Yao, S.Y. Qu, and H.Y. Che, 3D printing support structure and design method, . U.S. Patent 2021197494, July 01, 2021
[7]
F. Obregon, C. Vaquette, S. Ivanovski, D.W. Hutmacher, and L.E. Bertassoni, "Three-dimensional bioprinting for regenerative dentistry and craniofacial tissue engineering", J. Dent. Res., vol. 94, no. S9, pp. 143S-152S, 2015.
[http://dx.doi.org/10.1177/0022034515588885] [PMID: 26124216]
[8]
B. Derby, "Printing and prototyping of tissues and scaffolds", Science, vol. 338, no. 6109, pp. 921-926, 2012.
[http://dx.doi.org/10.1126/science.1226340] [PMID: 23161993]
[9]
J.S. Lin, "Application of virtual reality in oral implantology", Mod. Med., vol. 17, no. 28, pp. 229-232, 2011.
[10]
S.J. Lee, K.H. Jang, L.S.W. Spangberg, E. Kim, I.I.Y. Jung, C.Y. Lee, and K.Y. Kum, "Three-dimensional visualization of a mandibular first molar with three distal roots using computer-aided rapid prototyping", Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod., vol. 101, no. 5, pp. 668-674, 2006.
[http://dx.doi.org/10.1016/j.tripleo.2005.06.013] [PMID: 16632282]
[11]
Z. B. Miao, "A 3D printing denture production process", C.N.Patent 111973300A, November 24, 2020.
[12]
T. Connert, M.S. Zehnder, M. Amato, R. Weiger, S. Kühl, and G. Krastl, "Microguided Endodontics: A method to achieve minimally inva-sive access cavity preparation and root canal location in mandibular incisors using a novel computer-guided technique", Int. Endod. J., vol. 51, no. 2, pp. 247-255, 2018.
[http://dx.doi.org/10.1111/iej.12809] [PMID: 28665514]
[13]
S. Huang, C.K. Liu, F. Guo, J. Chai, Y. Zhu, and N. Liu, "A preparation method of 3D printed porous root-shaped dental implants", C.N. Patent 109620437A, May 04 2021.
[14]
L. Niu, and D. P. Niu, "A preparation method for 3D printing implants", C.N. Patent 112451136B, February 18, 2022.
[15]
Z.Y. Qu, Q. Wang, Y. Zhao, L.L. Sheng, W.D. Ma, and W.G. Qu, "Application of bone-supported 3D printing guide plate in maxillary LeFort type I osteotomy", West China J. Stomatol., vol. 36, pp. 60-65, 2018.
[PMID: 29594998]
[16]
Y.F. Liu, W.N. Wang, H. Yu, R. Ma, B. Wu, and B. Gao, "Study on the suitability of selective laser melting titanium alloy removable partial denture brackets", J. Pract. Stomatol., vol. 33, pp. 302-305, 2017.
[17]
H. Chen, H. Wang, P.J. Lv, Y. Wang, and Y.C. Sun, "Quantitative evaluation of tissue surface adaption of CAD-designed and 3D printed wax pattern of maxillary complete denture", Biomed Res. Int, vol. 2015, 2015.
[18]
Y. Qian, "3D prints movable artificial tooth of restoreing", C.N.Patent 216318111U, April 19 2022.
[19]
D. C. Lin, "A 3D printed porcelain tooth", C.N. Patent 215839611U, February 18 2022.
[20]
X.J. Liu, D.W. Yang, G. Fan, Q. Wang, G. Lu, and D.J. Fu, "Study on the effect of 3D printing technology on the accuracy of dental im-plants and patient satisfaction", J. Clinic. Stomatol., vol. 37, pp. 622-625, 2021.
[21]
M.T. Kattadiyil, C.J. Goodacre, and N.Z. Baba, "CAD/CAM complete dentures: A review of two commercial fabrication systems", J. Calif. Dent. Assoc., vol. 41, no. 6, pp. 407-416, 2013.
[PMID: 23875432]
[22]
C. Mangano, F. Mangano, J.A. Shibli, G. Luongo, M. De Franco, F. Briguglio, M. Figliuzzi, T. Eccellente, C. Rapani, M. Piombino, and A. Macchi, "Prospective clinical evaluation of 201 direct laser metal forming implants: Results from a 1-year multicenter study", Lasers Med. Sci., vol. 27, no. 1, pp. 181-189, 2012.
[http://dx.doi.org/10.1007/s10103-011-0904-3] [PMID: 21519945]
[23]
C. Mangano, F.G. Mangano, J.A. Shibli, M. Ricci, V. Perrotti, S. d’Avila, and A. Piattelli, "Immediate loading of mandibular overdentures supported by unsplinted direct laser metal-forming implants: Results from a 1-year prospective study", J. Periodontol., vol. 83, no. 1, pp. 70-78, 2012.
[http://dx.doi.org/10.1902/jop.2011.110079] [PMID: 21627459]
[24]
F. Mangano, S. Pozzi-Taubert, P.A. Zecca, G. Luongo, R.L. Sammons, and C. Mangano, "Immediate restoration of fixed partial prostheses supported by one-piece narrow-diameter selective laser sintering implants: A 2-year prospective study in the posterior jaws of 16 pa-tients", Implant Dent., vol. 22, no. 4, pp. 388-393, 2013.
[http://dx.doi.org/10.1097/ID.0b013e31829afa9d] [PMID: 23823735]
[25]
A. Dawood, B.M. Marti, V. Sauret-Jackson, A. Darwood, and B.D. Journal, "3D printing in dentistry", Br. Dent. J., vol. 219, no. 11, pp. 521-529, 2015.
[http://dx.doi.org/10.1038/sj.bdj.2015.914] [PMID: 26657435]
[26]
S.J. Luo, "Research on digital manufacturing of orthoses based on 3D printing", M.S. thesis, Xi'an Engineering University, Shaanxi Xi'an, China, 2019.
[27]
Y.L. Zhuang, "Application of 3D printing technology in the design and manufacture of extracorporeal devices for assisted limb rehabilita-tion", J. Guiyang Uni., vol. 16, pp. 81-85, 2021.
[28]
W.M. Zhang, D. Zhang, B. Yang, X.W. Zhou, and L.Y. Liu, "Observation on the efficacy of Pingle bone-setting manipulation reduction combined with 3D printing-assisted balloon design of external fixation brace in the treatment of distal radius fractures", J. Shanxi Uni. Tradi. Chinese Med., vol. 22, pp. 126-128, 2021.
[29]
Q. Y. Yu, H. Zhai, Y. X. Zhu, R. Z. Zhong, and T. L. Wang, "A 3D printed wrist joint adjustable fixation support", C.N. Patent 207666740U, July 31 2018.
[30]
J. W. Wang, W. Wang, G. H. Shi, H. Wang, C. P. Wang, T. Y. Liu, H. Y. Feng, W. Q. Yu, F. C. Ren, and K. R. Dai, "3D printed wrist ortho-sis", C.N. Patent 216257714U, April 12 2022.
[31]
Z. Y. Xu, and Y. D. Lu, "Phalangeal fracture reduction brace that 3D printed", C.N. Patent 214966464U, December 03 2021.
[32]
K. Ayguli, "Application of 3D printing technology in orthopedic surgery assistance", M.S. thesis, Xinjiang University, Urumqi, Xinjiang, China, 2017.
[33]
H.S. Nam, C.H. Seo, S.Y. Joo, D.H. Kim, and D.S. Park, "The application of three-dimensional printed finger splints for post hand burn patients: A case series investigation", Ann. Rehabil. Med., vol. 42, no. 4, pp. 634-638, 2018.
[http://dx.doi.org/10.5535/arm.2018.42.4.634] [PMID: 30180536]
[34]
Y. S. Xu, Y. S. Qi, B. G. Wei, B. X. Ma, and P. F. Zhang, "A highly elastic knee brace based on 3D printing", J.P. Patent 21606197U, August 11 1997.
[35]
W. Q. Li, W. T. Zhang, J. Liu, W. J. Liu, M. F. Meng, and Y. L. Zhang, "Customized foot external fixation protective tool based on 3D prin-ting", C.N. Patent 111839869A, October 30 2020.
[36]
G.M. Asadullah, N. Sabyrov, M.A.S. Kamal, and M. Hazrat Ali, "Design of a fluid-driven 3D printed spinal posture corrector", Mater. Today Proc., vol. 44, pp. 1555-1559, 2021.
[http://dx.doi.org/10.1016/j.matpr.2020.11.774]
[37]
F. Liu, B. Qiu, X.D. Xue, M.J. Zhang, L. Yang, and X.H. Xu, "Design of personalized external fixation brace based on 3D printing techno-logy", Chinese J. Ortho. Surg., vol. 24, pp. 2260-2263, 2016.
[38]
Z.J. Zhang, "Design method and application of 3D printing rehabilitation external fixation brace", M.S. thesis, Inner Mongolia University of Technology, Hohhot, Inner Mongolia, China, 2021.
[39]
Y. Li, "Method for reconstructing bone joint surface and repairing implant through 3D printing", C.N. Patent 112494177A, March 16 2021.
[40]
W. Z. Wu, J. Zhao, Z. H. Jiang, H. B. Zhang, and D. Zhao, "The 3D of Polyether-ether-ketobiomimetic biomimetic artificial bone prints ma-nufacture method", C.N. Patent 103707507B, August 17 2016.
[41]
B. B. Peng, S. G. Li, J. Guo, and Q. L. Zhao, 3D printing bone material and preparation method thereof, . ", C. N. Patent 113755021A, December 07, 2021.
[42]
R.J. Ferguson, A.J.R. Palmer, A. Taylor, M.L. Porter, H. Malchau, and S. Glyn-Jones, "Hip replacement", Lancet, vol. 392, no. 10158, pp. 1662-1671, 2018.
[http://dx.doi.org/10.1016/S0140-6736(18)31777-X] [PMID: 30496081]
[43]
T. Eisler, O. Svensson, A. Tengström, and E. Elmstedt, "Patient expectation and satisfaction in revision total hip arthroplasty", J. Arthroplasty, vol. 17, no. 4, pp. 457-462, 2002.
[http://dx.doi.org/10.1054/arth.2002.31245] [PMID: 12066276]
[44]
S.Y. Yin, and R. Pei, "Effect analysis of total hip arthroplasty in the treatment of developmental hip dysplasia", Chinese Foreign Med. Res., vol. 20, pp. 121-124, 2022.
[45]
K. Zou, and W. Luo, "“Application of 3D printing technology in hip arthroplasty”, Chinese", J. Med. Phys., vol. 38, pp. 436-440, 2021.
[46]
K.W. Tian, and K. Chen, "Application of 3D printing technology in total hip arthroplasty in the treatment of acetabular fracture complicated with avascular necrosis of femoral head and traumatic arthritis", Tradit. Chinese Med. Bone Set., vol. 29, pp. 42-44, 2017.
[47]
C. Sambhu, L. Sean, D.S. Arturo, and R.L. Andrew, "Custom matched joint prosthesis replacement", U.S. Patent 2016296289, October 13 2016.
[48]
G. Y. Liu, "3D prints knee joint auxiliary device for replacement convenient to patient is fixed", C. N. Patent 211796927U, October 30 2020.
[49]
X.K. Gao, "Application of 3D printing personalized osteotomy template in TKA", M.S. thesis, Hebei University of engineering, Handan City, Hebei Province, China, 2019.
[50]
L. Shi, "Application of 3D printing technology in physical model exchange in complex knee arthroplasty", Sci. Technol. Innov, pp. 26-27, 2021.
[51]
R.Y. Yan, "Application of 3D printed personalized osteotomy guide assisted total knee arthroplasty", J. Clinic. Ration. Drug Use, vol. 13, pp. 122-123, 2020.
[52]
J.S. Jiang, and Y. Zhao, "Clinical analysis of 3D printed osteotomy guide assisted knee arthroplasty in the treatment of unilateral knee os-teoarthritis", Zhejiang Trauma Surgery, vol. 23, pp. 769-771, 2018.
[53]
K.J. Hu, and W. Wang, "Research progress of artificial shoulder prosthesis design and related anatomy", Chinese J. Clinic. Anatomy, pp. 103-105, 2007.
[54]
A.M. Xian, B. Lu, Y. Wang, and P. Liu, "“Application of 3D printing technology in total shoulder arthroplasty for shoulder osteoarthritis”, Chinese", J. Shoulder Elbow Surg., pp. 105-114, 2018.
[55]
W. Zhao, M.M.T. Miradili, A. Baoerjiang, H. Yuan, and L. Wang, "Application of 3D printed navigation template and personalized custo-mized prosthesis in 3 cases of complex joint replacement", Chinese J. Bone Joint Injury, vol. 36, pp. 882-884, 2021.
[56]
Y.Q. Xu, M.G. Song, X.Y. Fan, X.B. Cai, T. Wang, W. Lin, C. Li, X.Q. He, Y. Chui, X. Li, Y.J. Huang, and S.Y. Zhou, "Design and clinical application of 3D printed microporous titanium artificial wrist joint", Chinese J. Joint Surgery, vol. 15, pp. 143-150, 2021.
[57]
J. C. Wang, Q. Han, Y. G. Qin, T. Yu, Y. Zou, and X. N. Wang, "3D prints full wrist joint of individuation customization", C.N. Patent 205307155U, June 15 2016.
[58]
D.F. Justin, V.B. Nguyen, and D.J. Medlin, "Composite joint arthroplasty systems and methods", U. S. Patent 2020054346, February 20 2020.
[59]
J.W. Wang, T. Li, Y.J. Xu, S. Li, Y. Ren, and K.R. Dai, "Biological 3D printing and organ reconstruction", J. Shanghai Jiaotong Univ., vol. 55, pp. 46-48, 2021.
[60]
Q. Jallerat, and A.W. Feinberg, "Extracellular matrix structure and composition in the early four-chambered embryonic heart", Cells, vol. 9, no. 2, p. 285, 2020.
[http://dx.doi.org/10.3390/cells9020285] [PMID: 31991580]
[61]
S. H. Li, Z. Q. Li, and X. J. Yao, "A kind of medical biotechnology 3d printing equipments", C.N. Patent 108032521B, October 29 2019.
[62]
S. Vijayavenkataraman, W.C. Yan, W.F. Lu, C.H. Wang, and J.Y.H. Fuh, "3D bioprinting of tissues and organs for regenerative medicine", Adv. Drug Deliv. Rev., vol. 132, pp. 296-332, 2018.
[http://dx.doi.org/10.1016/j.addr.2018.07.004] [PMID: 29990578]
[63]
W.L. Ng, C.K. Chua, and Y.F. Shen, "Print me an organ! Why we are not there yet", Progr. Polymer Sci, vol. 97, 2019.
[64]
Y. He, L. L. Chen, and L. Shao, "Biological 3D printing method of large tissue", C.N. Patent 112917891A.
[65]
X.Y. Yue, T.C. Shi, and J.H. Qiu, "A new source of organ transplantation: Organ printing", Chin. J. Coal Ind. Med., pp. 408-410, 2008.
[66]
S. Wang, H. C. Wu, and Y. K. Su, "Application of 3D printing software organ model in medical operation simulation", C. N. Patent 114078354A, February 22 2022.
[67]
Z. Shen, G. Xiong, and Y. Xie, "Medical model based on 3D printing and its manufacturing method", C.N. Patent 109345932B, September 28 2021.
[68]
B. L. Wang, "A 3D printing device for human organ model", C. N. Patent 205202186U, May 04 2016.
[69]
S. Constance, and S. Andreas, "Method for 3D printing of vascularized tissues and organs", C. N. Patent 114206587A, March 18 2022.
[70]
L. Hao, "Scientists printed a realistic heart valve model in 3D", Biomedical Engineering and Clinic. vol. 24, pp. 703, 2020.
[71]
N. Noor, A. Shapira, R. Eddri, I. Gal, L. Wertheim, and T. Dvir, "3D printing of personalized thick and perfusable cardiac patches and hearts", Adv. Sci, vol. 6, 2019.
[http://dx.doi.org/10.1002/advs.201900344]
[72]
Y. Cheng, Z.W. Hu, and N.G. Dong, "Clinical application of 3D printing technology in congenital heart disease", J. Clin. Surg., pp. 1203-1205, 2021.
[73]
I. Wamala, J. Brüning, J. Dittmann, S. Jerichow, J. Weinhold, L. Goubergritis, A. Hennemuth, V. Falk, and J. Kempfert, "Simulation of a right anterior thoracotomy access for aortic valve replacement using a 3D printed model", Innovations, vol. 14, no. 5, pp. 428-435, 2019.
[http://dx.doi.org/10.1177/1556984519870510] [PMID: 31431151]
[74]
L. Y. Huang, Q. Zhang, Y. Chen, and M. P. Huang, "Device and method for preoperative evaluation of congenital heart disease operation scheme with 3D printing", C.N. Patent 106361429B, September 11 2018.
[75]
X.Q. Zhang, Y. Li, L.W. Tan, and S.X. Zhang, "Construction of three-dimensional model of human heart fiber skeleton and valve and application of 3D printing model", J. Third Military Med. Uni., vol. 40, pp. 1251-1257, 2018.
[76]
K. Owais, A. Pal, R. Matyal, M. Montealegre-Gallegos, K.R. Khabbaz, A. Maslow, P. Panzica, and F. Mahmood, "Three-dimensional prin-ting of the mitral annulus using echocardiographic data: Science fiction or in the operating room next door?", J. Cardiothorac. Vasc. Anesth., vol. 28, no. 5, pp. 1393-1396, 2014.
[http://dx.doi.org/10.1053/j.jvca.2014.04.001] [PMID: 25281050]
[77]
H. Kizawa, E. Nagao, M. Shimamura, G. Zhang, and H. Torii, "Scaffold-free 3D bio-printed human liver tissue stably maintains metabolic functions useful for drug discovery", Biochem. Biophys. Rep., vol. 10, pp. 186-191, 2017.
[http://dx.doi.org/10.1016/j.bbrep.2017.04.004] [PMID: 28955746]
[78]
S.S. Chen, M.Y. Hu, R.C. Shi, T.B. Zhou, and Q. Shi, "Preliminary application of 3D printing technology in complex liver lesions", China Digital Med, pp. 74-75, 2019.
[79]
Y. Xiao, "Study on protein synthesis function of three-dimensional bioprinted liver organoid model", PhD. thesis, Peking Union Medical College, Beijing, China , 2021.
[80]
N.N. Zein, I.A. Hanouneh, P.D. Bishop, M. Samaan, B. Eghtesad, C. Quintini, C. Miller, L. Yerian, and R. Klatte, "Three-dimensional print of a liver for preoperative planning in living donor liver transplantation", Liver Transpl., vol. 19, no. 12, pp. 1304-1310, 2013.
[http://dx.doi.org/10.1002/lt.23729] [PMID: 23959637]
[81]
K. Takagi, A. Nanashima, T. Abo, J. Arai, N. Matsuo, T. Fukuda, and T. Nagayasu, "Three-dimensional printing model of liver for opera-tive simulation in perihilar cholangiocarcinoma", Hepatogastroenterology, vol. 61, no. 136, pp. 2315-2316, 2014.
[PMID: 25699373]
[82]
L. Carolo, "3D Printed Kidney: The Latest Advancements", All3DP, 2019. Available from: https://all3dp.com/2/3d-printed-kidney-the-latest-advancements
[83]
X.T. Han, L.B. Yang, X.H. Li, P. Wei, W.W. Lv, H. Zhang, and J.T. Sun, "Application of 3D printing technology in retroperitoneal laparos-copic nephron sparing surgery for renal tumors", J. Clin. Urol., vol. 32, pp. 866-869, 2017.
[84]
G.B. Zhao, X. Liu, Y.H. Tang, H.W. Su, H.B. Ling, C. Feng, C.Y. Li, X.D. Li, Y. Wang, and X.L. Zhu, "Effect analysis of 3D printing mo-del of kidney assisted percutaneous nephrolithotomy for complex renal calculi", Chin. Med., pp. 1862-1865, 2019.
[85]
P.V. Glybochko, L.M. Rapoport, Y.G. Alyaev, E.S. Sirota, E.A. Bezrukov, D.N. Fiev, I.S. Byadretdinov, M.D. Bukatov, A.V. Letunovskiy, and D.O. Korolev, "Multiple application of three-dimensional soft kidney models with localized kidney cancer: A pilot study", Urologia, vol. 85, no. 3, pp. 99-105, 2018.
[http://dx.doi.org/10.1177/0391560317749405] [PMID: 30117386]
[86]
V. Mironov, N. Reis, and B. Derby, "Review: Bioprinting: A beginning", Tissue Eng., vol. 12, no. 4, pp. 631-634, 2006.
[http://dx.doi.org/10.1089/ten.2006.12.631] [PMID: 16674278]
[87]
T.H. Ang, F.S.A. Sultana, D.W. Hutmacher, Y.S. Wong, J.Y.H. Fuh, X.M. Mo, H.T. Loh, E. Burdet, and S.H. Teoh, "Fabrication of 3D chitosan–hydroxyapatite scaffolds using a robotic dispensing system", Mater. Sci. Eng. C, vol. 20, no. 1-2, pp. 35-42, 2002.
[http://dx.doi.org/10.1016/S0928-4931(02)00010-3]
[88]
X. Wang, "Overview on biocompatibilities of implantable biomaterials", In: R. Lazinica, Ed., Advances in Biomaterials Science and Bio-medical Applications in Biomedicine., 2013, pp. 111-155.
[http://dx.doi.org/10.5772/53461]
[89]
X. Wang, J. Tuomi, and A.A. Mäkitie, "The integrations of biomaterials and rapid prototyping techniques for intelligent manufacturing of complex organs", In: R. Lazinica, Ed., Advances in Biomaterials Science and Applications in Biomedicine., 2013, pp. 437-463.
[http://dx.doi.org/10.5772/53114]
[90]
W. Q. Hao, H. Z. Zheng, X. X. Liu, and X. J. Wu Jun, "A 3D printing method for organ ultrasonic modeling", C.N. Patent 110349255A, October 18 2010.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy