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Current Drug Safety

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ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

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Case Report

A Case of de novo Annular-plaque Type Psoriasis Following Oxford- AstraZeneca COVID-19 Vaccination

Author(s): Namrata Chhabra* and Anju George

Volume 18, Issue 4, 2023

Published on: 21 September, 2022

Page: [584 - 588] Pages: 5

DOI: 10.2174/1574886317666220613163327

Price: $65

Abstract

Background: There have been increasing reported cases of new-onset or aggravation of pre-existing dermatoses after the implementation of COVID-19 vaccination.

Case Presentation: An elderly male was presented with multiple annular scaly plaques all over the body two weeks following administration of the first dose of Oxford-AstraZeneca COVID-19 vaccine. The lesions further aggravated after taking the second dose of the vaccine. The clinical and histopathology features were suggestive of annular plaque psoriasis.

Conclusion: We report this first case of de novo plaque psoriasis following the Oxford- AstraZeneca COVID-19 vaccine, and it signifies a potential side effect of autoimmune reactivation after COVID vaccination.

Keywords: Psoriasis, COVID-19 vaccine, annular, astrazeneca, hypertension, psoriasis.

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Graphical Abstract

[1]
McMahon DE, Amerson E, Rosenbach M, et al. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. J Am Acad Dermatol 2021; 85(1): 46-55.
[http://dx.doi.org/10.1016/j.jaad.2021.03.092] [PMID: 33838206]
[2]
Ewer KJ, Barrett JR, Belij-Rammerstorfer S, et al. T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial. Nat Med 2021; 27(2): 270-8.
[http://dx.doi.org/10.1038/s41591-020-01194-5] [PMID: 33335323]
[3]
Elamin S, Hinds F, Tolland J. De novo generalized pustular psoriasis following Oxford-AstraZeneca COVID-19 vaccine. Clin Exp Dermatol 2022; 47(1): 153-5.
[http://dx.doi.org/10.1111/ced.14895] [PMID: 34398977]
[4]
Lehmann M, Schorno P, Hunger RE, Heidemeyer K, Feldmeyer L, Yawalkar N. New onset of mainly guttate psoriasis after COVID-19 vaccination: A case report. J Eur Acad Dermatol Venereol 2021; 35(11): e752-5.
[http://dx.doi.org/10.1111/jdv.17561] [PMID: 34309932]
[5]
Krajewski PK, Matusiak Ł, Szepietowski JC. Psoriasis flare-up associated with second dose of Pfizer-BioNTech BNT16B2b2 COVID-19 mRNA vaccine. J Eur Acad Dermatol Venereol 2021; 35(10): e632-4.
[http://dx.doi.org/10.1111/jdv.17449] [PMID: 34131967]
[6]
Onsun N, Kaya G, Işık BG, Güneş B. A generalized pustular psoriasis flare after CoronaVac COVID-19 vaccination: Case report. Health Promot Perspect 2021; 11(2): 261-2.
[http://dx.doi.org/10.34172/hpp.2021.32] [PMID: 34195051]
[7]
Perna D, Jones J, Schadt CR. Acute generalized pustular psoriasis exacerbated by the COVID-19 vaccine. JAAD Case Rep 2021; 17: 1-3.
[http://dx.doi.org/10.1016/j.jdcr.2021.08.035] [PMID: 34522741]
[8]
Fang WC, Chiu LW, Hu SC. Psoriasis exacerbation after first dose of AstraZeneca coronavirus disease 2019 vaccine. J Dermatol 2021; 48(11): e566-7.
[http://dx.doi.org/10.1111/1346-8138.16137] [PMID: 34487570]
[9]
Sotiriou E, Tsentemeidou A, Bakirtzi K, Lallas A, Ioannides D, Vakirlis E. Psoriasis exacerbation after COVID-19 vaccination: A report of 14 cases from a single centre. J Eur Acad Dermatol Venereol 2021; 35(12): e857-9.
[http://dx.doi.org/10.1111/jdv.17582] [PMID: 34363647]
[10]
Bostan E, Elmas L, Yel B, Yalici-Armagan B. Exacerbation of plaque psoriasis after inactivated and BNT162b2 mRNA COVID-19 vaccines: A report of two cases. Dermatol Ther 2021; 34(6): e15110.
[http://dx.doi.org/10.1111/dth.15110] [PMID: 34427024]
[11]
Mieczkowska K, Kaubisch A, McLellan BN. Exacerbation of psoriasis following COVID-19 vaccination in a patient previously treated with PD-1 inhibitor. Dermatol Ther 2021; 34(5): e15055.
[http://dx.doi.org/10.1111/dth.15055] [PMID: 34231301]
[12]
Quattrini L, Verardi L, Caldarola G, Peluso G, De Simone C, D’Agostino M. New onset of remitting seronegative symmetrical synovitis with pitting oedema and palmoplantar psoriasis flare-up after Sars-Cov-2 vaccination. J Eur Acad Dermatol Venereol 2021; 35(11): e727-9.
[http://dx.doi.org/10.1111/jdv.17502] [PMID: 34236728]

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