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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Occurrence, Synthesis and Biosynthesis of Bacterial Heptoses

Author(s): Paul Kosma

Volume 12, Issue 12, 2008

Page: [1021 - 1039] Pages: 19

DOI: 10.2174/138527208785161169

Price: $65

Abstract

Heptoses are important higher-carbon sugars occurring in numerous structural variations in several domains of the bacterial cell wall, which are briefly summarized. Recent approaches towards the chemical and chemo-enzymatic synthesis of these microbial monosaccharides will be summarized as well as progress made in the elucidation of two major biochemical pathways involving the synthesis of heptose phosphates and nucleotide-activated heptoses.

Keywords: Bacterial Heptoses, Biosynthesis, Synthesis, bacterial cell wall, microbial monosaccharides, Lipopolysaccharides


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