Acute Myocardial Infarction in Hemophilia A with HIV and Hyperhomocysteinemia-
A Rare Case Report

Arjun      Kachhwaha; Amit   Kumar   Rohila; Swapnil      Tripathi; Durga   Shankar   Meena; Satyendra      Khichar; Deepak      Kumar

Abstract

Background: Patients with hemophilia have a hypocoagulable state and less chances of thrombus formation. Therefore, they are expected to have a lower cardiovascular mortality than the general population. The lower cardiovascular mortality can be explained by less chances of thrombus formation due to hypocoagulability.

Case Presentation: Here, we present a case of a 42-year-old male patient who presented with severe chest pain radiating to the back for 4 days. ECG was suggestive of recent acute anteroseptal myocardial infarction. There was a history of receiving intravenous recombinant factor VIII, 1 hour prior to the onset of chest pain for knee joint swelling. The occurrence of acute coronary syndromes in patients with hemophilia A is uncommon and rarely reported.

Conclusion: Here, we report a patient with severe hemophilia A who developed acute myocardial infarction after administration of recombinant factor VIII.

Keywords: Acute Myocardial Infarction, cardiovascular mortality, intravenous recombinant factor, hemophilia, HIV Patient, hyperhomocysteinemia.

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DOI https://dx.doi.org/10.2174/1871529X22666220126122458	Print ISSN 1871-529X
Publisher Name Bentham Science Publisher	Online ISSN 2212-4063

Cardiovascular & Hematological Disorders-Drug Targets

Acute Myocardial Infarction in Hemophilia A with HIV and Hyperhomocysteinemia- A Rare Case Report

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