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Current Topics in Medicinal Chemistry

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ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Review Article

Stimulants and Depressor Drugs in the Sleep-wake Cycle Modulation: The Case of Alcohol and Cannabinoids

Author(s): Eric Murillo-Rodríguez*, Cristina Carreón, Mario Eduardo Acosta-Hernández and Fabio García-García*

Volume 22, Issue 15, 2022

Published on: 15 February, 2022

Page: [1270 - 1279] Pages: 10

DOI: 10.2174/1568026622666220105105054

Price: $65

Abstract

A complex neurobiological network drives the sleep-wake cycle. In addition, external stimuli, including stimulants or depressor drugs, also influence the control of sleep. Here we review the recent advances that contribute to the comprehensive understanding of the actions of stimulants and depressor compounds, such as alcohol and cannabis, in sleep regulation. The objective of this review is to highlight the neurobiological mechanism engaged by alcohol and cannabis in sleep control.

Keywords: Alcohol, Cannabinoids, Caffeine, Sleep, Thalamus, Wakefulness.

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