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Current Drug Safety

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ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

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Case Report

Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report

Author(s): Verinder Sharma*, Sapna Sharma and Minakshi Doobay

Volume 17, Issue 3, 2022

Published on: 14 January, 2022

Page: [278 - 280] Pages: 3

DOI: 10.2174/1574886316666211013120735

Price: $65

Abstract

Background: In this report, we describe a case of domperidone withdrawal in a woman with a history of major depressive disorder and obsessive-compulsive disorder (OCD), who experienced a recurrence of these disorders after stopping domperidone.

Case Presentation: The symptoms improved after the restarting of domperidone and disappeared gradually as the drug was tapered and discontinued. Clinicians should consider domperidone withdrawal a differential diagnosis in women with a history of depression or anxiety who present with an acute onset of these symptoms following the abrupt discontinuation of domperidone.

Conclusion: A gradual taper off of the drug may be effective in minimizing withdrawal symptoms and obviate the need for psychotropic drug use.

Keywords: Domperidone, lactation, withdrawal-induced, depression, OCD, galactagogue.

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Graphical Abstract

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