Abstract
Radical chemistry is known for two centuries. Due to the fascinating nature of the radical-mediated processes, these reactions have attracted the attention of organic chemists to prepare new compounds with diverse stereochemistry. Radical-induced methods mostly follow atom economical principles. Tin-based radical annulation method is the most common and widely used procedure for the synthesis of a wide range of organic compounds with medicinal significance. In this review, we report recent stereoselective tin-mediated radical cyclization reactions. The versatility of tinbased reagents in the cyclization process as reported herein will encourage chemists to construct many other molecules of interest following the principles involved in these reactions.
Keywords: Carbon-carbon bond, tin, annulation, radical cyclization, stereochemistry, radical mediated.
Current Organic Chemistry
Title:Tin-mediated Radical Cyclization Reactions
Volume: 25 Issue: 22
Author(s): Saima malik*, Aditya G. Lavekar and Bimal Krishna Banik*
Affiliation:
- Department of Chemistry, Panjab University, Sector-14, Chandigarh,India
- College of Sciences and Human Studies; Prince Mohammad Bin Fahd University, P.O. Box 1664; Al Khobar 31952,Saudi Arabia
Keywords: Carbon-carbon bond, tin, annulation, radical cyclization, stereochemistry, radical mediated.
Abstract: Radical chemistry is known for two centuries. Due to the fascinating nature of the radical-mediated processes, these reactions have attracted the attention of organic chemists to prepare new compounds with diverse stereochemistry. Radical-induced methods mostly follow atom economical principles. Tin-based radical annulation method is the most common and widely used procedure for the synthesis of a wide range of organic compounds with medicinal significance. In this review, we report recent stereoselective tin-mediated radical cyclization reactions. The versatility of tinbased reagents in the cyclization process as reported herein will encourage chemists to construct many other molecules of interest following the principles involved in these reactions.
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Cite this article as:
malik Saima*, Lavekar G. Aditya and Banik Krishna Bimal*, Tin-mediated Radical Cyclization Reactions, Current Organic Chemistry 2021; 25 (22) . https://dx.doi.org/10.2174/1385272825666210617165918
DOI https://dx.doi.org/10.2174/1385272825666210617165918 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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