Generic placeholder image

Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Research Article

Chemical Variability and Antioxidant Activities of the Essential Oils of the Aerial Parts of Ammoides verticillata and the Roots of Carthamus caeruleus and their Synergistic Effect in Combination

Author(s): Imane Rihab Mami, Noria Merad-Boussalah, Mohammed El Amine Dib*, Boufeldja Tabti, Jean Costa and Alain Muselli

Volume 24, Issue 1, 2021

Published on: 06 June, 2020

Page: [71 - 78] Pages: 8

DOI: 10.2174/1386207323666200606213057

Price: $65

Abstract

Aim and Objective: Oxidative stress is implicated in the development and progression of many diseases. Some of the appropriate actions that could taken to resolve the problem of these diseases are search for new antioxidant substances isolated from plants. The aims of this study were to research the intraspecies variations of A. verticillata and C. caeruleus essential oils from 8 locations using statistical analysis, the in vitro antioxidant properties of collective essential oils and in combinations.

Materials and Methods: The essential oils were analyzed by GC and GC-MS. The intraspecies variations of the essential oil compositions were discussed using principal component analysis (PCA) and cluster analysis (CA). The antioxidant properties were evaluated DPPH-radical scavenging activity and β-carotene bleaching test.

Results: The main components of Ammoides verticillata collective essential oil (Coll EO) were thymol (30.5%), carvacrol (23.2%), p-cymene (13.1%), limonene (12.5%) and terpinene-4-ol (12.3%). While roots of Carthamus caeruleus essential oil were dominated by carline oxide (86.2%). The chemical variability allowed the discrimination of two main Groups for both Coll EOs. A direct correlation between the altitudes, climate and the chemical compositions was evidenced. Ammoides verticulata and Carthamus caeruleus Coll Eos showed good antioxidant activity. In binary mixture, the interaction between both Coll Eos and between oils rich of thymol and/or carvacrol with carlina oxide produced the best synergistic effects compared to individual essential oils and the synthetic antioxidant (BHT).

Conclusion: Ammoides verticillata and Carthamus caeruleus essential oil blends can be used as a natural food preservative and alternative to chemical antioxidants.

Keywords: Collective essential oils, antioxidant activities, synergistic effects, carlina oxide, thymol, carvacrol.

[1]
Halliwell, B.; Gutteridge, J.M. The antioxidants of human extracellular fluids. Arch. Biochem. Biophys., 1990, 280(1), 1-8.
[http://dx.doi.org/10.1016/0003-9861(90)90510-6] [PMID: 2191627]
[2]
Lobo, V.; Patil, A.; Phatak, A.; Chandra, N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn. Rev., 2010, 4(8), 118-126.
[http://dx.doi.org/10.4103/0973-7847.70902] [PMID: 22228951]
[3]
Zarkovic, N. 4-hydroxynonenal as a bioactive marker of pathophysiological processes. Mol. Aspects Med., 2003, 24(4-5), 281-291.
[http://dx.doi.org/10.1016/S0098-2997(03)00023-2] [PMID: 12893006]
[4]
DeAngelis, L.M. Brain tumors. N. Engl. J. Med., 2001, 344(2), 114-123.
[http://dx.doi.org/10.1056/NEJM200101113440207] [PMID: 11150363]
[5]
Vági, E.; Rapavi, E.; Hadolin, M.; Vásárhelyiné Perédi, K.; Balázs, A.; Blázovics, A.; Simándi, B. Phenolic and triterpenoid antioxidants from Origanum majorana L. herb and extracts obtained with different solvents. J. Agric. Food Chem., 2005, 53(1), 17-21.
[http://dx.doi.org/10.1021/jf048777p] [PMID: 15631502]
[6]
Burt, S. Essential oils: their antibacterial properties and potential applications in foods--a review. Int. J. Food Microbiol., 2004, 94(3), 223-253.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2004.03.022] [PMID: 15246235]
[7]
Dayan, F.E.; Cantrell, C.L.; Duke, S.O. Natural products in crop protection. Bioorg. Med. Chem., 2009, 17(12), 4022-4034.
[http://dx.doi.org/10.1016/j.bmc.2009.01.046] [PMID: 19216080]
[8]
Felidj, M.; Bouazza, M.; Ferouani, T. Short paper about the floristic community and the interest of Ammoides pussila (verticillata), a medicinal plant from Mounts of Tlemcen National Park (Western Algeria). Geo Eco Trop, 2010, 34, 147-154.
[9]
Attou, A.; Davenne, D.; Benmansour, A.; Lazouni, H.A. Chemical composition and biological activities of Ammoides verticillata essential oil from West Algeria. Phytotherapie, 2017, 17(1), 2-8.
[http://dx.doi.org/10.3166/phyto-2019-0116]
[10]
El Ouariachi, M.; Tomi, P.; Bouyanzer, A.; Hammouti, B.; Desjobert, J.M.; Costa, J.; Paolini, J. Chemical composition and antioxidant activity of essential oils and solvent extracts of Ptychotis verticillata from Morocco. Food Chem. Toxicol., 2011, 49(2), 533-536.
[http://dx.doi.org/10.1016/j.fct.2010.11.019] [PMID: 21093522]
[11]
Chahal, K.K.; Dhaiwal, K.; Kumar, A.; Kataria, D.; Singla, N. Chemical composition of Trachyspermum ammi L. and its biological properties: A review. J. Pharmacogn. Phytochem., 2017, 6(3), 131-140.
[12]
Balbaa, S.I.; Hilal, S.H.; Haggag, M.Y. The volatile oil from the herb and fruits of Carum copticum at different stages of growth. Planta Med., 1973, 23(4), 312-320.
[http://dx.doi.org/10.1055/s-0028-1099450] [PMID: 4732115]
[13]
Belabbes, R.; Mami, I.R.; Dib, M.E.A.; Mejdoub, K.; Tabti, B.; Costa, J.; Muselli, A. Chemical composition and biological activities of essential oils of Echinops spinosus and Carlina vulgaris rich in polyacetylene compounds. Curr. Nutr. Food Sci., 2019, 16(4), 563-570.
[http://dx.doi.org/10.2174/1573401315666190206142929]
[14]
Saffidine, K.; Sahli, F.; Zerroug, M. Antimicrobial activity of an Algerian medicinal plant: Carthamus caeruleus L. Pharmacogn. Commun., 2013, 3(4), 71-76.
[15]
Mami, I.R.; Belabbes, R.; Dib, M.E.A.; Tabti, B.; Costa, J.; Muselli, A. Biological activities of carlina oxide isolated from the roots of Carthamus caeruleus. Nat. Prod. J., 2019, 10(2), 145-152.
[http://dx.doi.org/10.2174/2210315509666190117152740]
[16]
Adams, R.P. Identification of essential oils by Capillary Gas Chromatography/Mass Spectroscopy; Allured Publ. Corp: Carol Stream; III, 2001.
[17]
Konig, W.; Joulain, D.; Hochmuth, D. Terpenoids and Related Constituents of Essential Oils; Library of Mass Finder 2.1; Institute of Organic Chemistry, University of Hamburg, 2001.
[18]
Mc Lafferty, F.; Stauffer, D. Wiley Register of Mass Spectral DataMass spectrometry library search system bench-Top/PBM. Version, 6th ed; , 1994.
[19]
Standards, N.I.O. Technology, PC Version 1.7 of The NIST/EPA/NIH Mass Spectral Library 1999.
[20]
Que, F.; Mao, L.; Pan, X. Antioxidant activities of five Chinese rice wines and the involvement of phenolic compounds. Food Res. Int., 2006, 39, 581-587.
[http://dx.doi.org/10.1016/j.foodres.2005.12.001]
[21]
Bougatef, A.; Hajji, M.; Balti, R.; Lassoued, I.; Triki-Ellouz, Y.; Nasri, M. Antioxidant and free radical-scavenging activities of smooth hound (Mustelus mustelus) muscle protein hydrolysates obtained by gastrointestinal proteases. Food Chem., 2009, 114, 1198-1205.
[http://dx.doi.org/10.1016/j.foodchem.2008.10.075]
[22]
Tefiani, C.; Riazi, A.; Youcefi, F.; Aazza, S.; Gago, C.; Faleiro, M.L.; Pedro, L.G.; Barroso, J.G.; Figueiredo, A.C.; Megías, C.; Cortés-Giraldo, I.; Vioque, J.; Miguel, M.G. Ammoides pusilla (Apiaceae) and Thymus munbyanus (Lamiaceae) from Algeria essential oils: Chemical composition, antimicrobial, antioxidant and antiproliferative activities. J. Essent. Oil Res., 2015, 27(2), 1-9.
[http://dx.doi.org/10.1080/10412905.2015.1006739]
[23]
Amerah, A.M.; Ouwehand, A.C. Essential Oils in Food Preservation, Flavor and Safety. Use of essential oils in poultry production; Elsevier, 2016, pp. 101-110.
[24]
Elgndi, M.A.; Filip, S.; Pavlić, B.; Vladić, J.; Stanojković, T.; Žižak, Ž.; Zeković, Z. Antioxidative and cytotoxic activity of essential oils and extracts of Satureja Montana L., Coriandrum sativum L. and Ocimum basilicum L. obtained by supercritical fluid extraction. J. Supercrit. Fluids, 2017, 128, 128-137.
[http://dx.doi.org/10.1016/j.supflu.2017.05.025]
[25]
Strzemski, M.; Wójciak-Kosior, M.; Sowa, I.; Agacka-Mołdoch, M.; Drączkowski, P.; Matosiuk, D.; Kurach, Ł.; Kocjan, R.; Dresler, S. Application of Raman spectroscopy for direct analysis of Carlina acanthifolia subsp. utzka root essential oil. Talanta, 2017, 174(174), 633-637.
[http://dx.doi.org/10.1016/j.talanta.2017.06.070] [PMID: 28738633]
[26]
Bohlmann, F.; Schusterp, A.; Meusel, H.A. Carlina oxide derivative from Carlina diae. Phytochemistry, 1981, 20(4), 823-824.
[http://dx.doi.org/10.1016/0031-9422(81)85186-2]
[27]
Mejdoub, K.; Mami, I.R.; Belabbes, R.; Dib, M.E.A. DJabou, N.; Tabti, B.; Benyelles, N.G.; Costa, J.; Muselli, A. Chemical variability of Atractylis gummifera essential oils at three developmental stages and investigation of their antioxidant, antifungal and insecticidal activities. Curr. Bioact. Compd., 2019.
[http://dx.doi.org/10.2174/1573407215666190126152112]
[28]
Herrmann, F.; Hamoud, R.; Sporer, F.; Tahrani, A.; Wink, M. Carlina oxide--a natural polyacetylene from Carlina acaulis (Asteraceae) with potent antitrypanosomal and antimicrobial properties. Planta Med., 2011, 77(17), 1905-1911.
[http://dx.doi.org/10.1055/s-0031-1279984] [PMID: 21678234]
[29]
Dordević, S.; Petrović, S.; Dobrić, S.; Milenković, M.; Vucićević, D.; Zizić, S.; Kukić, J. Antimicrobial, anti-inflammatory, anti-ulcer and antioxidant activities of Carlina acanthifolia root essential oil. J. Ethnopharmacol., 2007, 109(3), 458-463.
[http://dx.doi.org/10.1016/j.jep.2006.08.021] [PMID: 17011148]
[30]
Link, P.; Roth, K.; Sporer, F.; Wink, M. Carlina acaulis exhibits antioxidant activity and counteracts Aβ toxicity in Caenorhabditis elegans. Molecules, 2016, 21(7), 871.
[http://dx.doi.org/10.3390/molecules21070871] [PMID: 27384550]
[31]
Grosso, C.; Oliveira, A.C.; Mainar, A.M.; Urieta, J.S.; Barroso, J.G.; Palavra, A.M. Antioxidant activities of the supercritical and conventional Satureja montana extracts. J. Food Sci., 2009, 74(9), C713-C717.
[http://dx.doi.org/10.1111/j.1750-3841.2009.01376.x] [PMID: 20492105]
[32]
Benyoucef, F.; Dib, M.E.A.; Arrar, Z.; Costa, J.; Muselli, A. synergistic antioxidant activity and chemical composition of essential oils from Thymus fontanesii, Artemisia herba-alba and Rosmarinus officinalis. J. Appl. Biotechnol. Rep., 2018, 5(4), 151-156.
[http://dx.doi.org/10.29252/JABR.05.04.03]
[33]
Bag, A.; Chattopadhyay, R.R. Evaluation of synergistic antibacterial and antioxidant efficacy of essential oils of spices and herbs in combination. PLoS One, 2015, 10(7)e0131321
[http://dx.doi.org/10.1371/journal.pone.0131321] [PMID: 26132146]
[34]
Sonam, K.S.; Guleria, S. Synergistic antioxidant activity of natural products. Ann. Pharmacol. Pharm., 2017, 2(8), 1086.

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy