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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Systematic Review Article

Standardisation of Technique and Volume of Iodinated Contrast Administration During Infrainguinal Angioplasty

Author(s): Kersten Morgan Bates, Huthayfa Ghanem, Julian Hague and Sean Joy Matheiken*

Volume 25 , Issue 44 , 2019

Page: [4667 - 4674] Pages: 8

DOI: 10.2174/1381612825666191209123821

Price: $65


Background: Acute Kidney injury is recognised to occur after administration of iodinated contrast during endovascular interventions for peripheral arterial disease. There are no standardised protocols for contrast delivery during infrainguinal angiography.

Objective: The objective of this paper is to review published practice regarding the technique of conventional infrainguinal angiography and intervention, and describe a standard set of subtraction views, injection rates and contrast volumes for infrainguinal angioplasty.

Methods: Database searches and review of papers containing (Angioplasty or Angiography) and (“lower limb” or peripheral or infrainguinal) and (method or technique or guidelines or protocol) was performed and defined procedures assessed.

Results: A small number of papers provided specific technical details relating to contrast volumes and angiography views. There was considerable variation from authors who have described the contrast volumes used for lower limb angiography. We describe our simple and consistent method. The precise pathophysiology of contrast related nephropathy is under scrutiny. There is interest in new technology to minimise contrast induced kidney injury.

Conclusion: Few publications specify iodinated contrast doses, injection volumes or imaging views for infrainguinal arteriography. Standard infrainguinal angioplasty can be performed with conventional equipment using relatively small volumes of contrast by following a systematic technique.

Keywords: Angiography, peripheral arterial disease, infra-inguinal, acute kidney injury, contrast-induced nephropathy, post-contrast AKI, global vascular guidelines.

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