Tetrabutyl ammonium fluoride (abbreviated as TBAF)-assisted palladium-catalyzed Suzuki reaction in neat
water has been demonstrated under the ligand and base-free conditions. The cross-coupling of aryl or heteroaryl bromides
with arylboronic acids generated the corresponding products in good to excellent yields in the presence of low concentration
of palladium acetate in combination with TBAF under air.
Keywords: Arylboronic acid, palladium, suzuki reaction, TBAF, water, N-heterocyclic carbenes, arylimines, ary(heteroaryl)oximes, Suzuki reaction, triphenylphosphine
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