Multivariate Image Analysis Applied to QSAR as a Tool for Mosquitoes Control: Dengue and Yellow Fever
Pp. 154-161 (8)
Matheus P. Freitas, Teodorico C. Ramalho, Elaine F. F. da Cunha and Rodrigo A. Cormanich
An image-based QSAR approach, called Multivariate Image Analysis Applied to Quantitative
Structure-Activity Relationships (MIA-QSAR) is described as a tool to model the toxicities of a series of
organotin compounds against Aedes aegypti and Anopheles stephensi mosquito larvae, vectors of dengue
and yellow fever. This methodology may help researchers to discover novel, potent mosquito controllers.
QSAR-2D, MIA-QSAR, dengue and yellow fever.
Department of Chemistry, Federal University of Lavras, P.O. Box 3037, 37200-000, Lavras, MG, Brazil