The Natural Products Journal

Francesco Epifano  
Università "G. D'Annunzio"
Chieti-Pescara, Chieti Scalo (CH)


Determination of Mercury and Other Metals in Red Yeast Rice

Author(s): Cynthia C. Smith, Amir A. Abdalla and Robert E. Smith

Affiliation: Total Diet and Pesticide Research Center, U. S. Food and Drug Administration, 11510 W 80th St, Lenexa, KS 66214, USA.


Chromium, arsenic, cadmium, nickel, selenium, mercury and lead have been determined in red yeast rice samples by ICP-MS and a Hydra-C mercury analyzer. Less than 0.010 μg/g mercury was found in all but one sample, which had 0.011 μg/g. The amounts of chromium, arsenic, cadmium, nickel, selenium, cadmium and lead varied from 0.05–0.83 (Cr), 0.05–0.35 (As), 0.004–0.139 (Cd), 0.13–2.05 (Ni), 0.028–0.222 (Se), and 0.000–0.517 (Pb) μg/g. Percent recoveries of spiked samples ranged from 77 – 111%. Recoveries of mercury in two different standard reference materials were 83 and 110%. The minimum detection limit and limit of quantitation for mercury were 0.2 and 1.0 ng, respectively.

Keywords: Mercury, arsenic, cadmium, lead, red yeast rice, ICP-MS, CVAAS, dietry suppliment, LDL, clomitrazole

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Article Details

Page: [114 - 117]
Pages: 4
DOI: 10.2174/2210315511202020114