Background: As populations age, screening instruments for cognitive impairment and dementia will become of
increasing importance in clinical practice. Mini-Mental Parkinson (MMP), a derivative of the Mini-Mental State Examination
(MMSE), was originally described as a cognitive screening instrument for use in Parkinson’s disease. Its item content
addresses some of the acknowledged shortcomings of the MMSE. Pragmatic use of MMP in general cognitive clinics has
not previously been examined.
Aim: To compare the performance of two scales, Mini-Mental Parkinson (MMP) and the Mini-Mental State Examination
(MMSE), as cognitive screening instruments for dementia in a memory clinic population.
Methods: MMP was administered prospectively to 201 consecutive new patient referrals independent of other tests used
to establish dementia diagnosis according to standard diagnostic criteria (DSM-IV). Diagnostic utility of MMP for dementia
was measured and compared with MMSE.
Results: MMP proved easy to use and acceptable to patients. Optimal test accuracy (0.86) was at MMP cutoff of ≤ 17/32,
with sensitivity 0.51, specificity 0.97, positive predictive value 0.83, negative predictive value 0.87, and area under Receiver
Operating Characteristic curve 0.89. Using a higher cutoff (≤ 29/32), MMP sensitivity was 1.00 with specificity
0.70. MMP scores correlated with MMSE (r = 0.93) and diagnostic agreement was high (κ = 0.85).
Conclusions: MMP is a useful screening instrument in the memory clinic setting, with patients who fall below the designated
cutoff requiring further investigation to ascertain a cause for their cognitive impairment.