Pp. 87-94 (8)
Hepatocellular carcinoma (HCC) is the most common primary liver cancer. HCC typically
develops in a cirrhotic liver and the overall survival is poor, primarily because the disease is often
diagnosed at an advanced stage, when curable treatment is no longer an option. Ideally, HCC lesions
should be detected when they are ≤ 2-3 cm in diameter. The diagnosis of HCC has improved with the
introduction of 4-phase contrast enhanced CT and dynamic, contrast enhanced MRI. However, for
small lesions, which are potentially curable, the detection rate remains poor. Molecular imaging of
specific metabolic pathways may provide new opportunities for early diagnosis of HCC.
Liver cancer; Cirrhosis; Contrast-enhanced CT; Dynamic MRI; PET.
PET Centre and Department of Medicine V, Aarhus University Hospital, Aarhus, Denmark