Stress Related Neuroendocrine Influences in Ovarian Cancer

Author(s): Yu Kang, Susan K. Lutgendorf, Wei Hu, Steven W. Cole, Anil K. Sood.

Journal Name:Current Cancer Therapy Reviews

Volume 8 , Issue 2 , 2012

Abstract:

A growing body of epidemiologic and clinical evidence points to a significant role of biobehavioral and associated neuroendocrine factors on cancer growth and progression. This review provides an overview of the emerging relationships between neuroendocrine pathways and ovarian cancer progression. The primary focus of this review is on the contributions of neuroendocrine influences on cancer cell biology and tumor microenvironment in ovarian cancer. This mechanistic understanding will inform new opportunities for pharmacological and behavioral interventions for improving the outcome of ovarian cancer patients.

Keywords: Neuroendocrine, Ovarian cancer, Stress, Angiogenesis, Anoikis

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Article Details

VOLUME: 8
ISSUE: 2
Year: 2012
Page: [100 - 109]
Pages: 10
DOI: 10.2174/157339412800675315
Price: $58