Stress Related Neuroendocrine Influences in Ovarian Cancer
Susan K. Lutgendorf,
Steven W. Cole,
Anil K. Sood.
A growing body of epidemiologic and clinical evidence points to a significant role of biobehavioral and associated
neuroendocrine factors on cancer growth and progression. This review provides an overview of the emerging relationships
between neuroendocrine pathways and ovarian cancer progression. The primary focus of this review is on the
contributions of neuroendocrine influences on cancer cell biology and tumor microenvironment in ovarian cancer. This
mechanistic understanding will inform new opportunities for pharmacological and behavioral interventions for improving
the outcome of ovarian cancer patients.
Keywords: Neuroendocrine, Ovarian cancer, Stress, Angiogenesis, Anoikis
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