Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety

Author(s): Cheng-Xia Tan, Yan-Xia Shi, Jian-Quan Weng, Xing-Hai Liu, Bao-Ju Li, Wei-Guang Zhao.

Journal Name: Letters in Drug Design & Discovery

Volume 9 , Issue 4 , 2012

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Abstract:

A new series of 1,2,4-triazoles containing cyclopropane moiety were synthesized and characterized by 1H NMR and elemental analyses. The biological activities results showed that most of them exhibited significant fungicidal activity towards six test fungi. Among them, several showed superiority over the commercial fungicide during the present study.

Keywords: 1, 2, 4-triazole, Cyclopropane, Antifungal activity, Synthesis, Microwave irradiation, Ultrasonic irradiation

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Article Details

VOLUME: 9
ISSUE: 4
Year: 2012
Page: [431 - 435]
Pages: 5
DOI: 10.2174/157018012799859954
Price: $58

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