Novel and highly stereoselective route to E-(but-1-en-3-yne-1-sulfonyl)hetarenes by palladium catalyzed Sonogashira type coupling of unstable E-2-chlorovinylsulfonylbenzene and E-2-(2-chlorovinylsulfonyl)pyridine was presented. Usage of potassium phosphate as novel base in Sonogashira reaction was demonstrated. Unusual coupling products in the Sonogashira reaction of E-2-(2-chlorovinylsulfanyl)benzothiazole with different alkynes were obtained.
Keywords: Copper catalysis, E-2-chlorovinylsulfonylhetarenes, E-(but-1-en-3-yne-1-sulfonyl)hetarenes, Palladium catalysis, Sonogashira coupling, dendrimers, triethylamine, salts, atom-numbering, atoms
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