Recent Patents on Biotechnology

Rongling Wu
Departments of Public Health Sciences and Statistics
Pennsylvania State College of Medicine
Hershey, PA


Biofilms: New Ideas for An Old Problem

Author(s): Carla C.C.R. de Carvalho

Affiliation: IBB-Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa, Portugal


Microbial cells, under moist conditions, are able to adhere to surfaces and to form structured communities embedded in a matrix of extracellular polymeric substances (EPS). In industrial environments, biofilms can cause heat and mass transfer limitations whilst in medical facilities they can be a source of contamination and proliferation of infections. Biofilm formation is related to the pathogenicity of some bacterial strains and cells in biofilms are usually resistant to antimicrobials agents, which increases the interest in new and sound methods for their prevention and destruction.

Keywords: Biofilm, micro-organism, exopolymeric matrix, decontamination, disinfection, deterrence, biocide, detergent, water supply, ultra-pure water, medical devices, haemodialysis, catheter, antimicrobial surface, cell adhesion.

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Article Details

Page: [13 - 22]
Pages: 10
DOI: 10.2174/187220812799789163