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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Zwittermicin A: A Promising Aminopolyol Antibiotic from Biocontrol Bacteria

Author(s): Estibaliz Sansinenea and Aurelio Ortiz

Volume 16, Issue 8, 2012

Page: [978 - 987] Pages: 10

DOI: 10.2174/138527212800194737

Price: $65

Abstract

(+)-Zwittermicin A is a highly polar, water-soluble aminopolyol antibiotic isolated from the soil-born bacterium B. cereus with significant activity against phytopathogenic fungi. The rising interest in zwittermicin A as a “green” biopesticide, has stimulated studies of its unique biosynthesis, mechanism of action and its organic synthesis. This review summarizes the current state of this antibiotic. A main focus of this review is the description of the chemistry of this compound including its synthesis.

Keywords: Zwittermicin A, Antibiotic, Biological control, Bacillus.


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