C-glycosylflavonoids represent a group of oxygen heterocyclic compounds found widespread in a variety of plants. Synthetic
organic chemists are now progressively utilizing C-glycosylflavonoid scaffolds due to their high biological potential. The present review
deals with advances in C-glycosylflavonoids research, namely establishing a new updated database of the natural occurrence of Cglycosylflavonoids
- one hundred and nine new structures have been reported up to 2011. The structural characterization of some novel
C-glycosylflavonoids from various plant species is also discussed. The reported organic synthetic routes along with the biosynthetic aspects
of C-glycosylflavonoids are also reviewed. Finally the paper underlines the wide range of C-glycosylflavonoid biological activity.
The mentioned topics are detailed in particular chapters and are supported in 187 references.
Keywords: Flavonoids, C-glycosylflavonoids, Mono-C-glycosylflavonoids, Di-C-glycosylflavonoids, O-glycosyl-C-glycosylflavonoids, Oacylated-
C-glycosylflavonoids, Mass spectrometry, 1D and 2D NMR spectroscopy, Synthesis, Biosynthesis, Metabolism, Biological activity;
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