Abstract
Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. This article aims to review the absorption, pharmacokinetics, distribution properties and toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.
Keywords: Liposomes, micelles, nanoparticles, PLGA, SLN, passive targeting, active targeting
Current Drug Metabolism
Title:Absorption, Pharmacokinetics and Disposition of Biodegradable Nanoscale Preparations
Volume: 13 Issue: 4
Author(s): Cheng Wang, Jing Wang, Tiezhu Chen, Zhiqiang Luo, Xuemei Yang, Xiongfei Pan, Yunfeng Lin, Zhiyong Qian and Xiaoxiao Cai
Affiliation:
Keywords: Liposomes, micelles, nanoparticles, PLGA, SLN, passive targeting, active targeting
Abstract: Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. This article aims to review the absorption, pharmacokinetics, distribution properties and toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.
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Cite this article as:
Wang Cheng, Wang Jing, Chen Tiezhu, Luo Zhiqiang, Yang Xuemei, Pan Xiongfei, Lin Yunfeng, Qian Zhiyong and Cai Xiaoxiao, Absorption, Pharmacokinetics and Disposition of Biodegradable Nanoscale Preparations, Current Drug Metabolism 2012; 13 (4) . https://dx.doi.org/10.2174/138920012800166508
DOI https://dx.doi.org/10.2174/138920012800166508 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
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