Chinese Herbs for Dementia Diseases

Author(s): H. M. Hugel, N. Jackson, B. H. May, C. C.I. Xue.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 12 , Issue 5 , 2012

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Abstract:

In the last twenty years a considerable body of information has accumulated on the chemical constituents of Chinese herbs and their therapeutic potential. Our evaluation/systematic review [1, 2] of well-designed, randomized double blind controlled trials on Chinese herbal medicines beneficial for the improvement of cognitive function revealed a range of either single herbs or herbal mixtures that provided neuroprotective benefits. Oxidative stress may directly initiate neurodegeneration and herbal antioxidant neuroprotection is considered as a preventative and therapeutic approach. We encountered Acoris gramineus rhizome (AGR), Panax ginseng, Polygala tenuifolia and Poria cocos as the four most frequently used herbs as single/herbal mixtures that were associated with positive cognitive enhancing outcomes. This review focuses on the evidence of their medicinal effects attributed to those constituents present in relatively high concentration.

Keywords: Acoris gramineus, P. ginseng, P. tenuifolia, Poria cocos, Alzheimer disease

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Article Details

VOLUME: 12
ISSUE: 5
Year: 2012
Page: [371 - 379]
Pages: 9
DOI: 10.2174/138955712800493951
Price: $58

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