Recent Patents on Catalysis (Discontinued)


Application of Chirally Modified Nickel Catalysts for Production of Optically Active Compounds

Author(s): Tsutomu Osawa and Victor Borovkov

Affiliation: Graduate School of Science and Engineering for Research, University of Toyama, Gofuku, Toyama 930- 8555, Japan.


The major patents concerning chirally modified nickel catalysts by enantiomerically pure tartaric acid are comprehensively surveyed. The methods of catalyst's preparation for attaining a high enantioselectivity and the synthetic routes for obtaining optically active compounds by using these tartaric acid-modified nickel catalysts are summarized. A recently claimed patent dealing with the robust chiral nickel catalyst, which exhibits an exceptionally high stability after preparation is also introduced.

Keywords: Asymmetric synthesis, chiral catalysts, chiral compounds, enantio-differentiating hydrogenation, methyl acetoacetate, modified nickel catalyst, nickel powder, Raney nickel, tartaric acid.

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Article Details

Page: [27 - 34]
Pages: 8
DOI: 10.2174/2211548X11201010027