The Natural Products Journal

Bin Wu
Zhejiang University
Hangzhou
China

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Opioid Alkaloids in Fire Poppies, Papaver Californicum

Author(s): James David Adams, Shin-Yu Lee, Julie Eunwoo Kim, Jirair Petrosyan, Mona Shahgholi, Roger Clemens.

Abstract:

P. Californicum (Papaveraceae), fire poppy, is traditionally used against pain. The seed pods were found to contain glycosides of 14-methylnormorphine and papaverine. The major alkaloid, ignimorphinan C67H80O19N2, is a mixture of sterol glycoside dimers of 14-methylnormorphine and papaverine. The second most abundant alkaloid, ignipapaverine C44H55O10N, is a sterol glycoside of papaverine. A possible glycoside of 2-methoxy-7-hydroxy-6-Omethyl- 7,8-dihydronormorphine-14-carbinol was found. Other compounds found were myricetin, malvidin-3-Oglucuronide and kaempferol acetate.

Keywords: P. Californicum, papaveraceae, fire poppy, alkaloid, 14-methylnormorphine, papaverine, Ignimorphinan, Ignipapaverine, opioids, sterol

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Article Details

VOLUME: 2
ISSUE: 1
Year: 2012
Page: [31 - 35]
Pages: 5
DOI: 10.2174/2210315511202010031