The Natural Products Journal

Bin Wu
Zhejiang University
Hangzhou
China

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Helicteres isora L.-“Mrigashringa”- Current Strategies and Future Aspects

Author(s): Varsha Tiwari, Anita Singh, Abhishek Tiwari.

Abstract:

Helicteres isora L. is an important medicinal plant which has been reported to posses phyto-constituents like alkaloida, glycosides, phytosterols, fixed oils and fats, phenolic compounds among which Cucurbitacin B and Isocucurbitacin B (cytotoxic principle) are of keen interest. Its diverse medicinal properties include anti-diabetic, anticancer, antispasmodic, anti-hyperglycemic, antioxidant, glycaemic control and renoprotective, glucose uptake activity, hypo-lipidaemic, antimicrobial, antifungal, anti-nociceptive, heart antioxidant, lipid peroxidation and hypoglycemic activities. This plant was commonly used in indigenous and traditional folk medicine system in South East Asia. An upto- date data on phytochemical composition and pharmacological properties of different parts of Helicteres isora are reviewed and commented in this article.

Keywords: Helicteres isora L, cucurbitacin B, cytotoxic, hypoglycemic, lipid peroxidation, renoprotective activity, β-sitosterol, anti-tumor activity, helisterculins A, flavonoid

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Article Details

VOLUME: 2
ISSUE: 1
Year: 2012
Page: [9 - 19]
Pages: 11
DOI: 10.2174/2210315511202010009