Title: Bioinspired Microchip Nanoporous Interferometric Sensor for Sensing and Biosensing Applications
VOLUME: 3 ISSUE: 4
Author(s):Tushar Kumeria, Luke Parkinson and Dusan Losic
Affiliation:Ian Wark Research Institute,University of South Australia Mawson Lakes, Adelaide SA 5095, Australia.
Keywords:Reflective interferometric spectroscopy, nanoporous alumina, microchip interference sensor, Fabry-Perot fringes, micro-chip devices, Refractive index, REFLACTIVE INTERFEROMETRIC, Fabrications, RIfS, AAO Sensor
Abstract: The design of a microfluidic nanoporous reflective interferometric (RIfS) sensor is presented. The key element of the sensor is a highly ordered nanoporous structure of anodic aluminium oxide (AAO) integrated into a microfluidic chip and combined with an optical fibre spectrophotometer and notebook computer. AAO with controlled pore dimensions was prepared by electrochemical anodization of aluminium using 0.3 M oxalic acid at 50V for 40 minutes. The performance of the microfluidic RIfS for sensing of surface binding reaction of alkanethiols (mercapto undecanoic acid) on gold is evaluated showing excellent sensitivity. The results show potential for development and application of interferometric label-free biosensing elements for a wide range of biomedical applications.
