Anti-Infective Agents

Anti-Infective Agents in Medicinal Chemistry

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2D- and 3D-QSAR Studies of Flavonoids, Biflavones and Chalcones: Antiviral, Antibacterial, Antifungal, and Antimycobacterial Activities

Author(s): Andrew G. Mercader, Alicia B. Pomilio.

Abstract:

Flavonoids comprise a group of naturally occurring compounds that are known by their biological properties. Antiviral, antibacterial, antifungal, and antimycobacterial activities were analyzed. The results were discussed in terms of the bioactivity tested, and the structure-activity relationship (SAR), bidimensional (2D)- and three-dimensional (3D)- quantitative structure-activity relationship (QSAR) studies carried out on flavones, flavanones, chalcones, and some biflavonoids.

Keywords: Antiviral, antibacterial, antifungal, antimycobacterial agents, biflavonoids, chalcones, 2D-QSAR, 3D-QSAR, flavones, flavanones

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Article Details

VOLUME: 10
ISSUE: 1
Year: 2012
Page: [41 - 54]
Pages: 14
DOI: 10.2174/2211362611201010041