Abstract
Age related muscle loss, known as sarcopenia, is a major factor in disability, loss of mobility and quality of life in the elderly. There are many proposed mechanisms of age-related muscle loss that include the endocrine system. A variety of hormones regulate growth, development and metabolism throughout the lifespan. Hormone activity may change with age as a result of reduced hormone secretion or decreased tissue responsiveness. This review will focus on the complex interplay between the endocrine system, aging and skeletal muscle and will present possible benefits of therapeutic interventions for sarcopenia.
Keywords: aging, endocrine, exercise, growth hormone, hormones, sarcopenia, testosterone, vitamin D, estrogen, muscle
Current Aging Science
Title: The Endocrine System and Sarcopenia: Potential Therapeutic Benefits
Volume: 4 Issue: 3
Author(s): Kevin L. McIntire and Andrew R. Hoffman
Affiliation:
Keywords: aging, endocrine, exercise, growth hormone, hormones, sarcopenia, testosterone, vitamin D, estrogen, muscle
Abstract: Age related muscle loss, known as sarcopenia, is a major factor in disability, loss of mobility and quality of life in the elderly. There are many proposed mechanisms of age-related muscle loss that include the endocrine system. A variety of hormones regulate growth, development and metabolism throughout the lifespan. Hormone activity may change with age as a result of reduced hormone secretion or decreased tissue responsiveness. This review will focus on the complex interplay between the endocrine system, aging and skeletal muscle and will present possible benefits of therapeutic interventions for sarcopenia.
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Cite this article as:
L. McIntire Kevin and R. Hoffman Andrew, The Endocrine System and Sarcopenia: Potential Therapeutic Benefits, Current Aging Science 2011; 4 (3) . https://dx.doi.org/10.2174/1874609811104030298
DOI https://dx.doi.org/10.2174/1874609811104030298 |
Print ISSN 1874-6098 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-6128 |
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