Current Aging Science

Prof. Debomoy K. Lahiri
Department of Psychiatry Indiana University School of Medicine
Indianapolis, IN
USA

Back

The Endocrine System and Sarcopenia: Potential Therapeutic Benefits

Author(s): Kevin L. McIntire, Andrew R. Hoffman.

Abstract:

Age related muscle loss, known as sarcopenia, is a major factor in disability, loss of mobility and quality of life in the elderly. There are many proposed mechanisms of age-related muscle loss that include the endocrine system. A variety of hormones regulate growth, development and metabolism throughout the lifespan. Hormone activity may change with age as a result of reduced hormone secretion or decreased tissue responsiveness. This review will focus on the complex interplay between the endocrine system, aging and skeletal muscle and will present possible benefits of therapeutic interventions for sarcopenia.

Keywords: aging, endocrine, exercise, growth hormone, hormones, sarcopenia, testosterone, vitamin D, estrogen, muscle

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

VOLUME: 4
ISSUE: 3
Year: 2011
Page: [298 - 305]
Pages: 8
DOI: 10.2174/1874609811104030298
Price: $58