Skin Regeneration: The Possibilities
Jack Penn, Addie O. Grobbelaar and Kerstin J. Rolfe
Affiliation: Institute for Plastic Surgery Research and Education, Dept. Plastic Surgery, The Royal Free Hospital, Pond Street, Hampstead, London, NW3 2QG, UK.
Scarring remains a large market with as yet no prescription medication to reduce or prevent scarring. Studies have indicated that early human fetuses can heal cutaneous wounds with perfect regeneration and a number of theories have been proposed for this regenerative phenotype. These theories and variations between fetal and adult wound healing have been studied and a number have been patented as future potential therapeutics to reduce or prevent scarring.
Keywords: Fetal wound healing, inflammation, regeneration, scar, TGF-β, wound healing
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