Current Aging Science

Prof. Debomoy K. Lahiri
Department of Psychiatry Indiana University School of Medicine
Indianapolis, IN


Effects of Music Therapy on Psychological Symptoms and Heart Rate Variability in Patients with Dementia. A Pilot Study

Author(s): Alfredo Raglio, Osmano Oasi, Marta Gianotti, Veronica Manzoni, Silvia Bolis, Maria C. Ubezio, Simona Gentile, Daniele Villani, Marco Stramba-Badiale.


We assessed the effects of music therapy (MT) on behavioral and psychological symptoms (BPSD) in dementia associated with changes in physiological parameters, as heart rate (HR) and heart rate variability (HRV). Twenty subjects were randomly assigned to MT treatment or standard care; all patients underwent neuropsychological assessment and ECG Holter recordings before and after the 15-week treatment. The treatment included 30 MT sessions. Depression significantly decreased (p=0.021) in the MT group. PNN50 improved in 50% patients of the MT group, but in none of the control group (p=0.013). MT may improve symptoms of depression and increase HRV in demented patients.

Keywords: BPSD, dementia, depression, Heart Rate Variability, music therapy, pNN50, antipsy-chotic agents, Agitation, heart rate, vascular dementia, beta blockers, percussions, glocken-spiels, xylophones, Synescope, Ela Medical, ADAS-cog, respiratory sinus arrhythmia, apathy, aberrant motor activity, night-time behavioral disturbances, autonomic nerv-ous system dysfunction

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Article Details

Year: 2010
Page: [242 - 246]
Pages: 5
DOI: 10.2174/1874609811003030242
Price: $58