Abstract
Background: The aim of the study was to evaluate correlation of breath holding index (BHI) as functional parameter for intracranial subclinical atherosclerotic changes - we have shown in our previous works and arterial stiffness (AS-functional parameter for extracranial subclinical atherosclerotic changes) in normal population. Patients and Methods: We included 120 healthy volunteers (conventional risk factors for cerebrovascular disease were excluded) who were examined at our Neurology Department. They were divided into 6 age groups-(25-35, 36-45, 46-55, 56-65, 66-75, 76+ years). We performed standard laboratory workup, body weight and height measurements, Color Doppler and Power Doppler of the main head and neck vessels and Transcranial Doppler, (measured by means of e-Tracking software). Results: There was decline of BHI, and increase in AS - in correlation with age increase (p < 0.01). There was statistically significant negative correlation between BHI and AS (r= -0,931, p < 0.01 right and r = -0,938, p < 0.01 left). Conclusion: These results show that decline in BHI as parameter for intracranial microvessel dysfunction is in good correlation with increase of AS as functional parameter of extracranial vascular aging.
Keywords: Arterial stiffness, breath holding index, aging
Current Aging Science
Title: Breath Holding Index and Arterial Stiffness as Markers of Vascular Aging
Volume: 3 Issue: 1
Author(s): Iris Zavoreo and Vida Demarin
Affiliation:
Keywords: Arterial stiffness, breath holding index, aging
Abstract: Background: The aim of the study was to evaluate correlation of breath holding index (BHI) as functional parameter for intracranial subclinical atherosclerotic changes - we have shown in our previous works and arterial stiffness (AS-functional parameter for extracranial subclinical atherosclerotic changes) in normal population. Patients and Methods: We included 120 healthy volunteers (conventional risk factors for cerebrovascular disease were excluded) who were examined at our Neurology Department. They were divided into 6 age groups-(25-35, 36-45, 46-55, 56-65, 66-75, 76+ years). We performed standard laboratory workup, body weight and height measurements, Color Doppler and Power Doppler of the main head and neck vessels and Transcranial Doppler, (measured by means of e-Tracking software). Results: There was decline of BHI, and increase in AS - in correlation with age increase (p < 0.01). There was statistically significant negative correlation between BHI and AS (r= -0,931, p < 0.01 right and r = -0,938, p < 0.01 left). Conclusion: These results show that decline in BHI as parameter for intracranial microvessel dysfunction is in good correlation with increase of AS as functional parameter of extracranial vascular aging.
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Cite this article as:
Zavoreo Iris and Demarin Vida, Breath Holding Index and Arterial Stiffness as Markers of Vascular Aging, Current Aging Science 2010; 3 (1) . https://dx.doi.org/10.2174/1874609811003010067
DOI https://dx.doi.org/10.2174/1874609811003010067 |
Print ISSN 1874-6098 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-6128 |
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