Fishing for Age-Related Visual System Mutants: Behavioral Screening of Retinal Degeneration Genes in Zebrafish

Author(s): Lei Li, Yuhao Li, Dongyan Chen, Jinping Shao, Xin le Li, Chen Xu.

Journal Name: Current Aging Science

Volume 3 , Issue 1 , 2010

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Abstract:

The zebrafish (Danio rerio) has recently become a mainstream model system for genetic studies of human diseases, such as neurological degenerative diseases, heart diseases, immuno-system disorders, etc. In this article, we will review some recent findings of the usefulness of zebrafish as a model vertebrate for behavioral screening of mutations in vertebrate visual system, for example, genes involved in age-related retinal degeneration.

Keywords: Neural degeneration, zebrafish, retina, mutation

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Article Details

VOLUME: 3
ISSUE: 1
Year: 2010
Page: [43 - 45]
Pages: 3
DOI: 10.2174/1874609811003010043

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