Gene Delivery System: A Developing Arena of Study for the New Era of Medicine
Saifur Rahman Khan,
Ravindra B. Malabadi,
Hoon H. Sunwoo,
Mavanur R. Suresh.
Gene therapy concept has been being overcome massive challenges from 1972 in ethical, socio-economical and developmental issues. In this review, we have attempted to go through almost all the arenas and described in a methodical way that reflects not only the initial ethical and scientific thoughts but also adorned a solid depiction of gene therapy related physico-chemical barriers, approaches and strategies till to date.
Keywords: Nanoparticles, plasmid DNA, transfection, targeting, vectors, vaccines, GENE DELIVERY, PLASMID BASED GENE EXPRESSION, Recombinant Adenovirus vector, Recombinant Retrovirus Vector, Recombinant Herpes Simplex Virus Vector, VIRUS INDEPENDENT GENE DELIVERY, HYBRID VECTORS, X-SCID
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