Epidermal Growth Factor Receptors: A Functional Perspective

Author(s): Petar M. Mitrasinovic.

Journal Name: Current Radiopharmaceuticals

Volume 5 , Issue 1 , 2012

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Abstract:

The epidermal growth factor receptors (EGFRs) belong to the ErbB family of receptor tyrosine kinases (TKs) involved in the proliferation of normal and malignant cells. EGFR has attracted considerable attention as a target for cancer therapy. This article considers various functional roles of EGFR-based systems that are relevant for the early detection and staging of cancers overexpressing EGFR.

Keywords: EGFR, tumor, imaging, targeting, peptide radiopharmaceutical, TUMORS, cancer

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Article Details

VOLUME: 5
ISSUE: 1
Year: 2012
Page: [29 - 33]
Pages: 5
DOI: 10.2174/1874471011205010029

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