Miniaturization in Biotechnology: Speeding up the Development of Bioprocesses

Author(s): Pedro Fernandes, Filipe Carvalho, Marco P.C. Marques.

Journal Name: Recent Patents on Biotechnology

Volume 5 , Issue 3 , 2011

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Abstract:

The use of miniaturized devices for fastening bioprocess development, even up to production scale, has expanded rapidly, a feature clearly noticeable in recent years. This matter was reviewed in a recent past, but several developments have occurred since. These will be addressed in the present work, which will provide some insight on the use of microfluidic /microstructured reactors and of micro-scale downstream processing as well, therefore broadening the scope of the review.

Keywords: Automation, biocatalysis, downstream processing, fermentation, high throughput, microfluidic devices, microreactors, microsensors, microstructured reactors, microtiter plates, Miniature bioreactors, Miniaturization in biotechnology, Monitoring and control of process variables, Optodes, Process intensification, shaken vessels

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Article Details

VOLUME: 5
ISSUE: 3
Year: 2011
Page: [160 - 173]
Pages: 14
DOI: 10.2174/187220811797579105
Price: $65

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