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Recent Patents on Biotechnology

Editor-in-Chief

ISSN (Print): 1872-2083
ISSN (Online): 2212-4012

Miniaturization in Biotechnology: Speeding up the Development of Bioprocesses

Author(s): Pedro Fernandes, Filipe Carvalho and Marco P.C. Marques

Volume 5, Issue 3, 2011

Page: [160 - 173] Pages: 14

DOI: 10.2174/187220811797579105

Price: $65

Abstract

The use of miniaturized devices for fastening bioprocess development, even up to production scale, has expanded rapidly, a feature clearly noticeable in recent years. This matter was reviewed in a recent past, but several developments have occurred since. These will be addressed in the present work, which will provide some insight on the use of microfluidic /microstructured reactors and of micro-scale downstream processing as well, therefore broadening the scope of the review.

Keywords: Automation, biocatalysis, downstream processing, fermentation, high throughput, microfluidic devices, microreactors, microsensors, microstructured reactors, microtiter plates, Miniature bioreactors, Miniaturization in biotechnology, Monitoring and control of process variables, Optodes, Process intensification, shaken vessels


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