Title: The Dynamic Face of HIV-1 Subtypes Among Men who have Sex with Men in Beijing, China
VOLUME: 9 ISSUE: 2
Author(s):Wanhai Wang, Jianqing Xu, Shulin Jiang, Kai Yang, Zhefeng Meng, Yan Ma, Mingkui Li, Xiaoxi Zhang, Yiming Shao, Fengmin Zhang and Xiaoyan Zhang
Affiliation:Department of Microbiology, Harbin Medical University, 194 Xuefu Road, Harbin 150086, China.
Keywords:HIV-1, MSM, molecular epidemiology, vaccine, subtype, recombinant, drug users, CRF01_AE dominates infection, transmitted infections
Abstract: The rapid increase of HIV-1 prevalence among Chinese men who have sex with men (MSM) provides an impetus for the acquisition of molecular epidemiologic information from this population. We conducted four serial crosssectional surveys during the years 2005-2009 and observed that the composition of HIV-1 subtypes was dynamically changing from clade B to CRF01_AE from years 2005-2009. HIV-1 infection in this population includes the persistent circulation of multiple HIV-1 subtypes and complex new recombinants.
