Regulatory T Cells in Atopic Dermatitis

Author(s): Naoki Oiso.

Journal Name: Recent Patents on Inflammation & Allergy Drug Discovery

Volume 4 , Issue 3 , 2010

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Abstract:

Atopic dermatitis is one of the most prevalent chronic eczematous inflammatory skin diseases in westernized populations. It is caused by both skin barrier dysfunction and abnormal immunologic response. An imbalance of effector T cells and regulatory T cells is a crucial factor in the initiation of allergic diseases. Recent advances in immunology have revealed the role of regulatory T cells in atopic dermatitis. Treatment of atopic dermatitis consists of restoring and maintaining a sufficient skin barrier and inducing a balanced systemic immune response.

Keywords: Regulatory T cells, atopic dermatitis

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Article Details

VOLUME: 4
ISSUE: 3
Year: 2010
Page: [244 - 248]
Pages: 5
DOI: 10.2174/187221310793564227
Price: $58

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PDF: 5