Current Drug Abuse Reviews

Joris C. Verster,
Utrecht University Utrecht Institute for Pharmaceutical Sciences
Division of Pharmacology
Utrecht
The Netherlands

Back

The Application of Minerals in Managing Alcohol Hangover: A Preliminary Review

Author(s): Jung-Ah Min, KyeSeong Lee and Dai-Jin Kim

Affiliation: Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, 505 Banpo-Dong, Seocho-Gu, Seoul, 137-701, Republic of Korea.

Abstract:

Despite the high prevalence and economic burden, biological mechanisms and effective treatments of alcohol hangover are not well understood. We have focused on oxidative stress and inflammatory responses which would substantially contribute to hangover physiology and symptoms based on preexisting research data. And, it is considered that minerals are one of the important components and influencing factors in antioxidant and anti-inflammatory system. Moreover, mineral deficient conditions show similar symptoms that occur in alcohol hangover. Herein we review some possible implications of various minerals, such as selenium, zinc, copper, vanadium, iron, and magnesium, according to suggested mechanisms and symptoms of alcohol hangover. Although, noticeable considerations and controlled trials will be required for general recommendations, we hope that our preliminary speculation would pave the way for further understanding and managing alcohol hangover.

Keywords: Alcohol, hangover, therapy, minerals, oxidative stress, inflammation, Antioxidant, Anti-inflammatory, Intoxication, Alcohol ingestion, Cardiac arrhythmias, Cardiovascular mortality, Toxicity, Congener, Alcohol consumption, Mood, cognition, Fatigue, Alcohol Metabolism, Acetaldehyde Toxicity, MEOS, ROS, Cigarette smoking, Pathogenesis, Glutathione peroxidase, ALDH, Alcohol-metabolizing enzymes, Cytokines, Prostaglandin, Hypoglycemia, Sleep disturbance, Vasodilation, Lipopolysaccharide, Anti-inflammatory cytokine, Alcohol intolerance, Alcohol Withdrawal, NMDA, Alcoholics, Fatigue syndrome, Blood glucose, Short-term memory, Alzheimer's disease, Synaptic plasticity, GAB, Long-term depression, Placebo, Homeostasis

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

VOLUME: 3
ISSUE: 2
Page: [110 - 115]
Pages: 6
DOI: 10.2174/1874473711003020110
Price: $58