Current Drug Abuse Reviews

Joris C. Verster,
Utrecht University Utrecht Institute for Pharmaceutical Sciences
Division of Pharmacology
The Netherlands


Treatment and Prevention of Alcohol Hangover

Author(s): Joris C. Verster and Renske Penning

Affiliation: Utrecht University, Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacology, Utrecht, The Netherlands.


The search for alcohol hangover cures is as old as alcohol itself. Many cures and prophylactic agents are available, but scientific evidence for their effectiveness is generally lacking. This review summarizes and discusses the limited number of studies that examined the effectiveness of alcohol hangover treatments. From these studies it must be concluded that most remedies do not significantly reduce overall hangover severity. Some compounds reduce specific symptoms such as vomiting and headache, but are not effective in reducing other common hangover symptoms such as drowsiness and fatigue. Hangover cures that showed positive effects were those inhibiting prostaglandin synthesis or accelerating alcohol metabolism. Future studies should elucidate the pathology of alcohol hangover. Until then, it is unlikely that an effective hangover cure will be developed.

Keywords: Alcohol hangover, cure, treatment, prophylactic, Alcohol, Prophylactic agents, Hangover treatments, Vomiting, Headache, Drowsiness, Fatigue, Alcohol metabolism, Alcohol consumption, Aspirin, Paracetamol, Tolfenamic acid, Prostaglandin, Migraine, Placebo, Propranolol, Alcohol detoxification, Chlormethiazole, Intoxication, Hangover symptoms, Nootropics, Pyritinol, Opuntia ficus indica (OFI), Heat shock protein, TEX-OE, Psychomotor, Alcohol-induced, C-reactive protein, KSS Formula, itrus tangerine Hort. et Tanaka, Zingiber officinale, Himalaya, Liv.52, Ayurvedic, Cappasis Spinosa, Cichorium intybus, Solanum nigrum, Cassia occidentalis, Terminalia arjuna, Achillea millefolium, Tamarix gallica, Phyllanthus amarus, Acetaldehyde, Artichoke Extract (LI120), Cynara scolymus, Vodka, Ethanol, Emblica officinalis, Andrographis paniculata, Phoenix dactylifera, Evodiae fructus, Asparagus officinalis, Echinosophora koreensis

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Article Details

Page: [103 - 109]
Pages: 7
DOI: 10.2174/1874473711003020103