Thin-layer Chromatography Methods for the Determination of Non- Steroidal Anti-inflammatory Drugs and Cephalosporin Antibiotics: A Review
Malgorzata Starek, Monika Dabrowska and Jerzy Skucinski
Affiliation: Jagiellonian University, Collegium Medicum, Department of Inorganic and Analytical Chemistry, 9 Medyczna Str., 30-688, Poland.
An extensive survey of the literature published in analytical and pharmaceutical chemistry journals has been conducted and the TLC methods which were developed and used for determination of non-steroidal anti-inflammatory drugs (NSAIDs) and cephalosporin antibiotics in bulk drugs, formulations and biological fluids have been reviewed. This review covers the time period from 1990 to 2008 during which over 120 TLC methods were reported. Presented review highlighted some recent patent developments and new TLC techniques that have been used in the analysis and detection of two different kinds of drugs.
Keywords: TLC, NSAIDs, cephalosporins, analytical methods, review
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