Abstract
In spite of optimal treatment of LDL - cholesterol, as per evidence -based guidelines, only a one third reduction in cardiovascular risk is achieved in our patients. This has led to the realization that other types of cholesterol, too, need to be treated, in order to achieve ideal cardiovascular health. The review focuses on high density lipoprotein (HDL) cholesterol as a target for treatment, its importance, relevant patents and current as well as future treatments.
Keywords: HDL cholesterol, hyperlipidemia, niacin, fibrates, statins
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title: HDL - Cholesterol: The New Target for Treatment
Volume: 4 Issue: 2
Author(s): Sanjay Kalra, Bharti Kalra, Navneet Agrawal and Ashraf Ganie
Affiliation:
Keywords: HDL cholesterol, hyperlipidemia, niacin, fibrates, statins
Abstract: In spite of optimal treatment of LDL - cholesterol, as per evidence -based guidelines, only a one third reduction in cardiovascular risk is achieved in our patients. This has led to the realization that other types of cholesterol, too, need to be treated, in order to achieve ideal cardiovascular health. The review focuses on high density lipoprotein (HDL) cholesterol as a target for treatment, its importance, relevant patents and current as well as future treatments.
Export Options
About this article
Cite this article as:
Kalra Sanjay, Kalra Bharti, Agrawal Navneet and Ganie Ashraf, HDL - Cholesterol: The New Target for Treatment, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2010; 4 (2) . https://dx.doi.org/10.2174/187221410791196605
DOI https://dx.doi.org/10.2174/187221410791196605 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
Related Articles
-
The Role of Dairy Products in Healthy Weight and Body Composition in Children and Adolescents
Current Nutrition & Food Science Surgical Ventricular Restoration: An Operation to Reverse Remodeling - Clinical Application (Part II) (Supplementry Table)
Current Cardiology Reviews Beneficial Role of Vitexin and Isovitexin Flavonoids in the Vascular Endothelium and Cardiovascular System
Current Nutraceuticals Editorial [Bioengineering and Clinical Perspectives in Diagnostic and Therapeutic Applications of Microbubbles (Executive Guest Editor: Theodore G. Papaioannou)]
Current Pharmaceutical Design Technological Innovations in Magnetic Resonance for Early Detection of Cardiovascular Diseases
Current Pharmaceutical Design Female Sexual Dysfunction: Therapeutic Options and Experimental Challenges
Cardiovascular & Hematological Agents in Medicinal Chemistry Opportunities and Challenges in Nano-structure Mediated Drug Delivery: Where Do We Stand?
Current Nanomedicine Psoriasis in Children: A Review
Current Pediatric Reviews “Endothelial Progenitor Cells” as a Therapeutic Strategy in Cardiovascular Disease
Current Vascular Pharmacology The Effect of Antihypertensive Drugs on Central Blood Pressure Beyond Peripheral Blood Pressure. Part II: Evidence for Specific Class-Effects of Antihypertensive Drugs on Pressure Amplification
Current Pharmaceutical Design The GH/IGF-1 Axis and Heart Failure
Current Cardiology Reviews Metabolic Homeostasis and Colonic Health: the Critical Role of Short Chain Fatty Acids
Current Nutrition & Food Science The LDL-Receptor and its Molecular Properties: From Theory to Novel Biochemical and Pharmacological Approaches in Reducing LDL-cholesterol
Current Medicinal Chemistry Future Prospects in Anti-Platelet Therapy: A Review of Potential P2Y12 and Thrombin Receptor Antagonists
Recent Patents on Cardiovascular Drug Discovery Association between Fragmentation and Various Substitution Features: A Study on Isoflavonoids Analogues by CID and HCD Using LTQ Orbitrap Mass Spectrometry
Current Traditional Medicine Rapid Screening of Antioxidant Active Constituents from Puerariae Lobatae Radix Based on the Investigation of Quantitative Patteren-Activity Relationship
Current Analytical Chemistry The Neuroprotective Effect of Ginkgo biloba Leaf Extract and its Possible Mechanism
Central Nervous System Agents in Medicinal Chemistry Polyphenols: Potential Future Arsenals in the Treatment of Diabetes
Current Pharmaceutical Design Vitamin E - Occurrence, Biosynthesis by Plants and Functions in Human Nutrition
Mini-Reviews in Medicinal Chemistry Amyloid A Amyloidosis Secondary to Rheumatoid Arthritis: An Uncommon Yet Important Complication
Current Rheumatology Reviews