Leptin as Clinical Target
Chunlin Cai, Fu-Dong Shi, Giuseppe Matarese and Antonio La Cava
Pages 160-166 (7)
Leptin is an adipocyte-derived hormone with pleiotropic effects on energy homeostasis, endocrine and reproductive functions, and immune responses. The multiple actions of leptin have led to the design and development of several leptin-based approaches to modulate the metabolic and endocrine status, to reduce inflammation, and to improve immune responses. Here, we review the current patents on leptin in different clinic applications.
Leptin, metabolism, therapeutics
Department of Medicine at the University of California Los Angeles, 1000 Veteran Avenue, Los Angeles, California 90095-1670, USA.