Recent Patents on Biotechnology

Nikolaos Labrou
Laboratory of Enzyme Technology, Department of Biotechnology
Agricultural University of Athens Iera Odos 75, Gr-118 55


Production and Application of Bacteriophage and Bacteriophage-Encoded Lysins

Author(s): Noemie M. Dorval Courchesne, Albert Parisien and Christopher Q. Lan

Affiliation: Department of Chemical and Biological Engineering, The University of Ottawa, Ottawa, ON, K1N 6N5, Canada.


The widespread resistance to antibiotics among pathogenic bacteria has made development of alternatives to antibiotics a pressing public concern. Extensive studies have established bacteriophages (phages) and phage-encoded lytic enzymes (virolysins) as two of the most promising families of alternative antibacterials for the treatment and prophylaxis of bacterial infections. They have shown great potential in veterinary and human medicine for the treatment and prophylaxis of infections. Technologies have also been patented employing phages and virolysins in other pathogen related applications including detection and decontamination.

Keywords: Virolysin, antibiotic resistance, lytic enzyme, lysin, bacteriophage

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Article Details

Page: [37 - 45]
Pages: 9
DOI: 10.2174/187220809787172678