Recent Patents on Drug Delivery & Formulation

Ryan F. Donnelly
School of Pharmacy
Queen's University Belfast


Trends in Pharmaceutical Taste Masking Technologies: A Patent Review

Author(s): Zelalem Ayenew, Vibha Puri, Lokesh Kumar and Arvind K. Bansal

Affiliation: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research(NIPER), Sector-67, S.A.S. Nagar, Punjab-160 062, India.


According to the year 2003 survey of pediatricians by the American Association of Pediatrics, unpleasant taste was the biggest barrier for completing treatment in pediatrics. The field of taste masking of active pharmaceutical ingredients(API) has been continuously evolving with varied technologies and new excipients. The article reviews the trends in taste masking technologies by studying the current state of the art patent database for the span of year 1997 to 2007. The worldwide database of European patent office( was employed to collect the patents and patent applications. It also discusses the possible reasons for the change of preferences in the taste masking technologies with time. The prime factors critical to the selection of an optimal taste masking technique such as the extent of drug bitterness, solubility, particle characteristics, dosage form and dose are briefly discussed.

Keywords: Taste masking, sweeteners, taste suppressants, taste potentiators

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Article Details

Page: [26 - 39]
Pages: 14
DOI: 10.2174/187221109787158364